Efficient variance components analysis across millions of genomes

Variance components analysis may be used for a variety of applications including heritability estimation and association mapping. Here, the authors present a computationally efficient method, scalable to extremely large GWAS datasets, and use it for heritabilty analysis of 22 traits from UK Biobank

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Autores principales: Ali Pazokitoroudi, Yue Wu, Kathryn S. Burch, Kangcheng Hou, Aaron Zhou, Bogdan Pasaniuc, Sriram Sankararaman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/044c5503786540658095e58fca2853be
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