Integrating Hi-C and FISH data for modeling of the 3D organization of chromosomes

Methodological advances have increased our understanding of chromatin structure through chromosome conformation capture techniques and high resolution imaging, but integration of these datasets is challenging. Here the authors propose GEM-FISH, a method for reconstructing the 3D models of chromosome...

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Autores principales: Ahmed Abbas, Xuan He, Jing Niu, Bin Zhou, Guangxiang Zhu, Tszshan Ma, Jiangpeikun Song, Juntao Gao, Michael Q. Zhang, Jianyang Zeng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/045621245b8a43758353a48a4ff3c3ac
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