Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets
Owais Gul,1 Saqib Gul2 1Department of Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan; 2Department of Medicine, Hamdard University, Karachi, PakistanWe read with great interest, the recently published article “Risk factors for developing dementia in type...
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Dove Medical Press
2019
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oai:doaj.org-article:04569ffa7c0742ec86d985ca399d27862021-12-02T00:48:19ZMild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets1178-2021https://doaj.org/article/04569ffa7c0742ec86d985ca399d27862019-02-01T00:00:00Zhttps://www.dovepress.com/letter-risk-factors-for-developing-dementia-in-type-2-diabetes-me-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Owais Gul,1 Saqib Gul2 1Department of Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan; 2Department of Medicine, Hamdard University, Karachi, PakistanWe read with great interest, the recently published article “Risk factors for developing dementia in type 2 diabetes mellitus patients with mild cognitive impairment” by Albai et al.1 The article provided a great insight into evaluating the prevalence of mild cognitive impairment (MCI) in patients with type 2 diabetes (T2DM) and highlighted the risk factors for conversion of MCI to dementia. We would like to add some knowledge of the mechanisms and pathogenesis of the development of MCI in T2DM patients and a guide to possible future therapeutic developments.View the original paper by Albai and colleagues.Gul OGul SDove Medical Pressarticlemild cognitive impairment (MCI)type 2 diabetes mellitus (T2DM)Dipeptidyl-4 peptidase (DPP4)Neurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 15, Pp 403-404 (2019) |
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DOAJ |
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topic |
mild cognitive impairment (MCI) type 2 diabetes mellitus (T2DM) Dipeptidyl-4 peptidase (DPP4) Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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mild cognitive impairment (MCI) type 2 diabetes mellitus (T2DM) Dipeptidyl-4 peptidase (DPP4) Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Gul O Gul S Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets |
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Owais Gul,1 Saqib Gul2 1Department of Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan; 2Department of Medicine, Hamdard University, Karachi, PakistanWe read with great interest, the recently published article “Risk factors for developing dementia in type 2 diabetes mellitus patients with mild cognitive impairment” by Albai et al.1 The article provided a great insight into evaluating the prevalence of mild cognitive impairment (MCI) in patients with type 2 diabetes (T2DM) and highlighted the risk factors for conversion of MCI to dementia. We would like to add some knowledge of the mechanisms and pathogenesis of the development of MCI in T2DM patients and a guide to possible future therapeutic developments.View the original paper by Albai and colleagues. |
format |
article |
author |
Gul O Gul S |
author_facet |
Gul O Gul S |
author_sort |
Gul O |
title |
Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets |
title_short |
Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets |
title_full |
Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets |
title_fullStr |
Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets |
title_full_unstemmed |
Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets |
title_sort |
mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of dpp4 activity and future possible therapeutic targets |
publisher |
Dove Medical Press |
publishDate |
2019 |
url |
https://doaj.org/article/04569ffa7c0742ec86d985ca399d2786 |
work_keys_str_mv |
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1718403475506724864 |