Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets

Owais Gul,1 Saqib Gul2 1Department of Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan; 2Department of Medicine, Hamdard University, Karachi, PakistanWe read with great interest, the recently published article “Risk factors for developing dementia in type...

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Autores principales: Gul O, Gul S
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Publicado: Dove Medical Press 2019
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spelling oai:doaj.org-article:04569ffa7c0742ec86d985ca399d27862021-12-02T00:48:19ZMild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets1178-2021https://doaj.org/article/04569ffa7c0742ec86d985ca399d27862019-02-01T00:00:00Zhttps://www.dovepress.com/letter-risk-factors-for-developing-dementia-in-type-2-diabetes-me-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Owais Gul,1 Saqib Gul2 1Department of Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan; 2Department of Medicine, Hamdard University, Karachi, PakistanWe read with great interest, the recently published article “Risk factors for developing dementia in type 2 diabetes mellitus patients with mild cognitive impairment” by Albai et al.1 The article provided a great insight into evaluating the prevalence of mild cognitive impairment (MCI) in patients with type 2 diabetes (T2DM) and highlighted the risk factors for conversion of MCI to dementia. We would like to add some knowledge of the mechanisms and pathogenesis of the development of MCI in T2DM patients and a guide to possible future therapeutic developments.View the original paper by Albai and colleagues.Gul OGul SDove Medical Pressarticlemild cognitive impairment (MCI)type 2 diabetes mellitus (T2DM)Dipeptidyl-4 peptidase (DPP4)Neurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 15, Pp 403-404 (2019)
institution DOAJ
collection DOAJ
language EN
topic mild cognitive impairment (MCI)
type 2 diabetes mellitus (T2DM)
Dipeptidyl-4 peptidase (DPP4)
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle mild cognitive impairment (MCI)
type 2 diabetes mellitus (T2DM)
Dipeptidyl-4 peptidase (DPP4)
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Gul O
Gul S
Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets
description Owais Gul,1 Saqib Gul2 1Department of Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan; 2Department of Medicine, Hamdard University, Karachi, PakistanWe read with great interest, the recently published article “Risk factors for developing dementia in type 2 diabetes mellitus patients with mild cognitive impairment” by Albai et al.1 The article provided a great insight into evaluating the prevalence of mild cognitive impairment (MCI) in patients with type 2 diabetes (T2DM) and highlighted the risk factors for conversion of MCI to dementia. We would like to add some knowledge of the mechanisms and pathogenesis of the development of MCI in T2DM patients and a guide to possible future therapeutic developments.View the original paper by Albai and colleagues.
format article
author Gul O
Gul S
author_facet Gul O
Gul S
author_sort Gul O
title Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets
title_short Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets
title_full Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets
title_fullStr Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets
title_full_unstemmed Mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of DPP4 activity and future possible therapeutic targets
title_sort mild cognitive decline in type 2 diabetes mellitus patients – risk factors and pathogenesis: role of dpp4 activity and future possible therapeutic targets
publisher Dove Medical Press
publishDate 2019
url https://doaj.org/article/04569ffa7c0742ec86d985ca399d2786
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