Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection

T cells compose a critical component of the immune response to coronavirus infection with SARS-CoV-2. Here the authors characterise the T cell response to SARS CoV-2 in patients and their close contacts, and show the presence of SARS-CoV-2 specific T cells in the absence of detectable virus infectio...

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Autores principales: Zhongfang Wang, Xiaoyun Yang, Jiaying Zhong, Yumin Zhou, Zhiqiang Tang, Haibo Zhou, Jun He, Xinyue Mei, Yonghong Tang, Bijia Lin, Zhenjun Chen, James McCluskey, Ji Yang, Alexandra J. Corbett, Pixin Ran
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0463342948204f80b1fa3e95c857eefe
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spelling oai:doaj.org-article:0463342948204f80b1fa3e95c857eefe2021-12-02T17:04:52ZExposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection10.1038/s41467-021-22036-z2041-1723https://doaj.org/article/0463342948204f80b1fa3e95c857eefe2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22036-zhttps://doaj.org/toc/2041-1723T cells compose a critical component of the immune response to coronavirus infection with SARS-CoV-2. Here the authors characterise the T cell response to SARS CoV-2 in patients and their close contacts, and show the presence of SARS-CoV-2 specific T cells in the absence of detectable virus infection.Zhongfang WangXiaoyun YangJiaying ZhongYumin ZhouZhiqiang TangHaibo ZhouJun HeXinyue MeiYonghong TangBijia LinZhenjun ChenJames McCluskeyJi YangAlexandra J. CorbettPixin RanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhongfang Wang
Xiaoyun Yang
Jiaying Zhong
Yumin Zhou
Zhiqiang Tang
Haibo Zhou
Jun He
Xinyue Mei
Yonghong Tang
Bijia Lin
Zhenjun Chen
James McCluskey
Ji Yang
Alexandra J. Corbett
Pixin Ran
Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection
description T cells compose a critical component of the immune response to coronavirus infection with SARS-CoV-2. Here the authors characterise the T cell response to SARS CoV-2 in patients and their close contacts, and show the presence of SARS-CoV-2 specific T cells in the absence of detectable virus infection.
format article
author Zhongfang Wang
Xiaoyun Yang
Jiaying Zhong
Yumin Zhou
Zhiqiang Tang
Haibo Zhou
Jun He
Xinyue Mei
Yonghong Tang
Bijia Lin
Zhenjun Chen
James McCluskey
Ji Yang
Alexandra J. Corbett
Pixin Ran
author_facet Zhongfang Wang
Xiaoyun Yang
Jiaying Zhong
Yumin Zhou
Zhiqiang Tang
Haibo Zhou
Jun He
Xinyue Mei
Yonghong Tang
Bijia Lin
Zhenjun Chen
James McCluskey
Ji Yang
Alexandra J. Corbett
Pixin Ran
author_sort Zhongfang Wang
title Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection
title_short Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection
title_full Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection
title_fullStr Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection
title_full_unstemmed Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection
title_sort exposure to sars-cov-2 generates t-cell memory in the absence of a detectable viral infection
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0463342948204f80b1fa3e95c857eefe
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