Severe Acute Motor Axonal Neuropathy Associated with Influenza-A (H1N1) Infection and Prolonged Respiratory Failure - A Case Report

Acute Motor Axonal Neuropathy (AMAN) is an immune-mediated disorder of the peripheral nervous system, part of the spectrum of the Guillain-Barre syndrome (GBS). An infectious event most often triggers it reported a few weeks before the onset. The reported case is of a 56 years-old woman who develope...

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Autores principales: Mosora Oana, Barcutean Laura, Balasa Rodica, Fodor Raluca, Maier Smaranda, Bajko Zoltan, Stoian Adina, Motataianu Anca
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Lenguaje:EN
Publicado: Sciendo 2021
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Acceso en línea:https://doaj.org/article/04652a300cdf45659f41ef90f56a7272
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spelling oai:doaj.org-article:04652a300cdf45659f41ef90f56a72722021-12-05T14:11:08ZSevere Acute Motor Axonal Neuropathy Associated with Influenza-A (H1N1) Infection and Prolonged Respiratory Failure - A Case Report2393-181710.2478/jccm-2021-0030https://doaj.org/article/04652a300cdf45659f41ef90f56a72722021-10-01T00:00:00Zhttps://doi.org/10.2478/jccm-2021-0030https://doaj.org/toc/2393-1817Acute Motor Axonal Neuropathy (AMAN) is an immune-mediated disorder of the peripheral nervous system, part of the spectrum of the Guillain-Barre syndrome (GBS). An infectious event most often triggers it reported a few weeks before the onset. The reported case is of a 56 years-old woman who developed acute motor axonal neuropathy three weeks after respiratory infection with influenza A virus subtype H1N1. Despite early treatment with plasmapheresis and intravenous immunoglobulins, the patient remained tetraplegic, mechanically ventilated for five months, with repetitive unsuccessful weaning trails. The probable cause was considered to be phrenic nerve palsy in the context of acute motor axonal neuropathy. This case highlights that acute motor axonal neuropathy is a severe and life-threatening form of Guillain-Barre syndrome associated with significant mortality and morbidity. Neurological and physical recovery strongly depend on the inter-professional effort in an intensive care unit and neurology professionals.Mosora OanaBarcutean LauraBalasa RodicaFodor RalucaMaier SmarandaBajko ZoltanStoian AdinaMotataianu AncaSciendoarticleguillain-barre syndromeacute motor axonal neuropathynodopathyinfluenza virus a h1n1tetraplegiaprolonged respiratory failureMedical emergencies. Critical care. Intensive care. First aidRC86-88.9ENThe Journal of Critical Care Medicine, Vol 7, Iss 4, Pp 302-307 (2021)
institution DOAJ
collection DOAJ
language EN
topic guillain-barre syndrome
acute motor axonal neuropathy
nodopathy
influenza virus a h1n1
tetraplegia
prolonged respiratory failure
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
spellingShingle guillain-barre syndrome
acute motor axonal neuropathy
nodopathy
influenza virus a h1n1
tetraplegia
prolonged respiratory failure
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
Mosora Oana
Barcutean Laura
Balasa Rodica
Fodor Raluca
Maier Smaranda
Bajko Zoltan
Stoian Adina
Motataianu Anca
Severe Acute Motor Axonal Neuropathy Associated with Influenza-A (H1N1) Infection and Prolonged Respiratory Failure - A Case Report
description Acute Motor Axonal Neuropathy (AMAN) is an immune-mediated disorder of the peripheral nervous system, part of the spectrum of the Guillain-Barre syndrome (GBS). An infectious event most often triggers it reported a few weeks before the onset. The reported case is of a 56 years-old woman who developed acute motor axonal neuropathy three weeks after respiratory infection with influenza A virus subtype H1N1. Despite early treatment with plasmapheresis and intravenous immunoglobulins, the patient remained tetraplegic, mechanically ventilated for five months, with repetitive unsuccessful weaning trails. The probable cause was considered to be phrenic nerve palsy in the context of acute motor axonal neuropathy. This case highlights that acute motor axonal neuropathy is a severe and life-threatening form of Guillain-Barre syndrome associated with significant mortality and morbidity. Neurological and physical recovery strongly depend on the inter-professional effort in an intensive care unit and neurology professionals.
format article
author Mosora Oana
Barcutean Laura
Balasa Rodica
Fodor Raluca
Maier Smaranda
Bajko Zoltan
Stoian Adina
Motataianu Anca
author_facet Mosora Oana
Barcutean Laura
Balasa Rodica
Fodor Raluca
Maier Smaranda
Bajko Zoltan
Stoian Adina
Motataianu Anca
author_sort Mosora Oana
title Severe Acute Motor Axonal Neuropathy Associated with Influenza-A (H1N1) Infection and Prolonged Respiratory Failure - A Case Report
title_short Severe Acute Motor Axonal Neuropathy Associated with Influenza-A (H1N1) Infection and Prolonged Respiratory Failure - A Case Report
title_full Severe Acute Motor Axonal Neuropathy Associated with Influenza-A (H1N1) Infection and Prolonged Respiratory Failure - A Case Report
title_fullStr Severe Acute Motor Axonal Neuropathy Associated with Influenza-A (H1N1) Infection and Prolonged Respiratory Failure - A Case Report
title_full_unstemmed Severe Acute Motor Axonal Neuropathy Associated with Influenza-A (H1N1) Infection and Prolonged Respiratory Failure - A Case Report
title_sort severe acute motor axonal neuropathy associated with influenza-a (h1n1) infection and prolonged respiratory failure - a case report
publisher Sciendo
publishDate 2021
url https://doaj.org/article/04652a300cdf45659f41ef90f56a7272
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