A computational approach to analyze the mechanism of action of the kinase inhibitor bafetinib.
Prediction of drug action in human cells is a major challenge in biomedical research. Additionally, there is strong interest in finding new applications for approved drugs and identifying potential side effects. We present a computational strategy to predict mechanisms, risks and potential new domai...
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Auteurs principaux: | Thomas R Burkard, Uwe Rix, Florian P Breitwieser, Giulio Superti-Furga, Jacques Colinge |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2010
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Accès en ligne: | https://doaj.org/article/046b9efec40442d3a2bc8198814632cf |
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