C. elegans chromosomes connect to centrosomes by anchoring into the spindle network

A connection between centrosomes and chromosomes is a key feature of mitotic spindles. Here the authors generate 3D reconstructions of whole mitotic spindles in earlyC. elegansembryos and show that chromosomes are anchored by the entire spindle network and that connections through kinetochore microt...

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Autores principales: Stefanie Redemann, Johannes Baumgart, Norbert Lindow, Michael Shelley, Ehssan Nazockdast, Andrea Kratz, Steffen Prohaska, Jan Brugués, Sebastian Fürthauer, Thomas Müller-Reichert
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/046e8d07808d493ab9b645788aa2c7ff
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spelling oai:doaj.org-article:046e8d07808d493ab9b645788aa2c7ff2021-12-02T17:01:24ZC. elegans chromosomes connect to centrosomes by anchoring into the spindle network10.1038/ncomms152882041-1723https://doaj.org/article/046e8d07808d493ab9b645788aa2c7ff2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15288https://doaj.org/toc/2041-1723A connection between centrosomes and chromosomes is a key feature of mitotic spindles. Here the authors generate 3D reconstructions of whole mitotic spindles in earlyC. elegansembryos and show that chromosomes are anchored by the entire spindle network and that connections through kinetochore microtubules are few and likely very transient.Stefanie RedemannJohannes BaumgartNorbert LindowMichael ShelleyEhssan NazockdastAndrea KratzSteffen ProhaskaJan BruguésSebastian FürthauerThomas Müller-ReichertNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stefanie Redemann
Johannes Baumgart
Norbert Lindow
Michael Shelley
Ehssan Nazockdast
Andrea Kratz
Steffen Prohaska
Jan Brugués
Sebastian Fürthauer
Thomas Müller-Reichert
C. elegans chromosomes connect to centrosomes by anchoring into the spindle network
description A connection between centrosomes and chromosomes is a key feature of mitotic spindles. Here the authors generate 3D reconstructions of whole mitotic spindles in earlyC. elegansembryos and show that chromosomes are anchored by the entire spindle network and that connections through kinetochore microtubules are few and likely very transient.
format article
author Stefanie Redemann
Johannes Baumgart
Norbert Lindow
Michael Shelley
Ehssan Nazockdast
Andrea Kratz
Steffen Prohaska
Jan Brugués
Sebastian Fürthauer
Thomas Müller-Reichert
author_facet Stefanie Redemann
Johannes Baumgart
Norbert Lindow
Michael Shelley
Ehssan Nazockdast
Andrea Kratz
Steffen Prohaska
Jan Brugués
Sebastian Fürthauer
Thomas Müller-Reichert
author_sort Stefanie Redemann
title C. elegans chromosomes connect to centrosomes by anchoring into the spindle network
title_short C. elegans chromosomes connect to centrosomes by anchoring into the spindle network
title_full C. elegans chromosomes connect to centrosomes by anchoring into the spindle network
title_fullStr C. elegans chromosomes connect to centrosomes by anchoring into the spindle network
title_full_unstemmed C. elegans chromosomes connect to centrosomes by anchoring into the spindle network
title_sort c. elegans chromosomes connect to centrosomes by anchoring into the spindle network
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/046e8d07808d493ab9b645788aa2c7ff
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