C. elegans chromosomes connect to centrosomes by anchoring into the spindle network
A connection between centrosomes and chromosomes is a key feature of mitotic spindles. Here the authors generate 3D reconstructions of whole mitotic spindles in earlyC. elegansembryos and show that chromosomes are anchored by the entire spindle network and that connections through kinetochore microt...
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Nature Portfolio
2017
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oai:doaj.org-article:046e8d07808d493ab9b645788aa2c7ff2021-12-02T17:01:24ZC. elegans chromosomes connect to centrosomes by anchoring into the spindle network10.1038/ncomms152882041-1723https://doaj.org/article/046e8d07808d493ab9b645788aa2c7ff2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15288https://doaj.org/toc/2041-1723A connection between centrosomes and chromosomes is a key feature of mitotic spindles. Here the authors generate 3D reconstructions of whole mitotic spindles in earlyC. elegansembryos and show that chromosomes are anchored by the entire spindle network and that connections through kinetochore microtubules are few and likely very transient.Stefanie RedemannJohannes BaumgartNorbert LindowMichael ShelleyEhssan NazockdastAndrea KratzSteffen ProhaskaJan BruguésSebastian FürthauerThomas Müller-ReichertNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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Science Q Stefanie Redemann Johannes Baumgart Norbert Lindow Michael Shelley Ehssan Nazockdast Andrea Kratz Steffen Prohaska Jan Brugués Sebastian Fürthauer Thomas Müller-Reichert C. elegans chromosomes connect to centrosomes by anchoring into the spindle network |
description |
A connection between centrosomes and chromosomes is a key feature of mitotic spindles. Here the authors generate 3D reconstructions of whole mitotic spindles in earlyC. elegansembryos and show that chromosomes are anchored by the entire spindle network and that connections through kinetochore microtubules are few and likely very transient. |
format |
article |
author |
Stefanie Redemann Johannes Baumgart Norbert Lindow Michael Shelley Ehssan Nazockdast Andrea Kratz Steffen Prohaska Jan Brugués Sebastian Fürthauer Thomas Müller-Reichert |
author_facet |
Stefanie Redemann Johannes Baumgart Norbert Lindow Michael Shelley Ehssan Nazockdast Andrea Kratz Steffen Prohaska Jan Brugués Sebastian Fürthauer Thomas Müller-Reichert |
author_sort |
Stefanie Redemann |
title |
C. elegans chromosomes connect to centrosomes by anchoring into the spindle network |
title_short |
C. elegans chromosomes connect to centrosomes by anchoring into the spindle network |
title_full |
C. elegans chromosomes connect to centrosomes by anchoring into the spindle network |
title_fullStr |
C. elegans chromosomes connect to centrosomes by anchoring into the spindle network |
title_full_unstemmed |
C. elegans chromosomes connect to centrosomes by anchoring into the spindle network |
title_sort |
c. elegans chromosomes connect to centrosomes by anchoring into the spindle network |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/046e8d07808d493ab9b645788aa2c7ff |
work_keys_str_mv |
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_version_ |
1718382127804841984 |