The gene repertoire of the main cysteine protease of Trypanosoma cruzi, cruzipain, reveals four sub-types with distinct active sites

The gene repertoire of the main cysteine protease of Trypanosoma cruzi, cruzipain, reveals four sub-types with distinct active sites

Abstract Cruzipains are the main papain-like cysteine proteases of Trypanosoma cruzi, the protozoan parasite that causes Chagas disease. Encoded by a multigenic family, previous studies have estimated the presence of dozens of copies spread over multiple chromosomes in different parasite strains. He...

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Autores principales: Viviane Corrêa Santos, Antonio Edson Rocha Oliveira, Augusto César Broilo Campos, João Luís Reis-Cunha, Daniella Castanheira Bartholomeu, Santuza Maria Ribeiro Teixeira, Ana Paula C. A. Lima, Rafaela Salgado Ferreira
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/04782922325f4c48a209e0ed361ee524
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