A Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure

MiRNA-regulated processes are pivotal in cardiovascular homeostasis and disease. These short non-coding RNAs have ideal properties that could be utilized as potential biomarkers; moreover, their functions as post-transcriptional regulators of mRNA make them interesting therapeutic targets. In this r...

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Autores principales:	Peter J. Kennel, P. Christian Schulze
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	MicroRNA miRNA cardiac biomarker heart failure antagomir Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/048793f8bac1484a9415aa671d57df8c
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spelling	oai:doaj.org-article:048793f8bac1484a9415aa671d57df8c2021-11-25T17:12:40ZA Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure10.3390/cells101131912073-4409https://doaj.org/article/048793f8bac1484a9415aa671d57df8c2021-11-01T00:00:00Zhttps://www.mdpi.com/2073-4409/10/11/3191https://doaj.org/toc/2073-4409MiRNA-regulated processes are pivotal in cardiovascular homeostasis and disease. These short non-coding RNAs have ideal properties that could be utilized as potential biomarkers; moreover, their functions as post-transcriptional regulators of mRNA make them interesting therapeutic targets. In this review, we summarize the current state of miRNA-based biomarkers in a variety of diseases leading to heart failure, as well as provide an outlook on developing miRNA-based therapies in the heart failure field.Peter J. KennelP. Christian SchulzeMDPI AGarticleMicroRNAmiRNAcardiac biomarkerheart failureantagomirBiology (General)QH301-705.5ENCells, Vol 10, Iss 3191, p 3191 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	MicroRNA miRNA cardiac biomarker heart failure antagomir Biology (General) QH301-705.5
spellingShingle	MicroRNA miRNA cardiac biomarker heart failure antagomir Biology (General) QH301-705.5 Peter J. Kennel P. Christian Schulze A Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure
description	MiRNA-regulated processes are pivotal in cardiovascular homeostasis and disease. These short non-coding RNAs have ideal properties that could be utilized as potential biomarkers; moreover, their functions as post-transcriptional regulators of mRNA make them interesting therapeutic targets. In this review, we summarize the current state of miRNA-based biomarkers in a variety of diseases leading to heart failure, as well as provide an outlook on developing miRNA-based therapies in the heart failure field.
format	article
author	Peter J. Kennel P. Christian Schulze
author_facet	Peter J. Kennel P. Christian Schulze
author_sort	Peter J. Kennel
title	A Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure
title_short	A Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure
title_full	A Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure
title_fullStr	A Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure
title_full_unstemmed	A Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure
title_sort	review on the evolving roles of mirna-based technologies in diagnosing and treating heart failure
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/048793f8bac1484a9415aa671d57df8c
work_keys_str_mv	AT peterjkennel areviewontheevolvingrolesofmirnabasedtechnologiesindiagnosingandtreatingheartfailure AT pchristianschulze areviewontheevolvingrolesofmirnabasedtechnologiesindiagnosingandtreatingheartfailure AT peterjkennel reviewontheevolvingrolesofmirnabasedtechnologiesindiagnosingandtreatingheartfailure AT pchristianschulze reviewontheevolvingrolesofmirnabasedtechnologiesindiagnosingandtreatingheartfailure
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A Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure

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