Plasmodium vivax infection compromises reticulocyte stability

During Plasmodium intra-erythrocytic developmental, parasites compromise the structural integrity of host red-blood cells. Here, Clark et al. develop a flow cytometric osmotic stability assay to show that P. vivax infection destabilizes host reticulocytes, which are less stable than P. falciparum-in...

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Autores principales:	Martha A. Clark, Usheer Kanjee, Gabriel W. Rangel, Laura Chery, Anjali Mascarenhas, Edwin Gomes, Pradipsinh K. Rathod, Carlo Brugnara, Marcelo U. Ferreira, Manoj T. Duraisingh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/048bfeac5af7438dad7b6d45ad8104b5
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spelling	oai:doaj.org-article:048bfeac5af7438dad7b6d45ad8104b52021-12-02T13:16:18ZPlasmodium vivax infection compromises reticulocyte stability10.1038/s41467-021-21886-x2041-1723https://doaj.org/article/048bfeac5af7438dad7b6d45ad8104b52021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21886-xhttps://doaj.org/toc/2041-1723During Plasmodium intra-erythrocytic developmental, parasites compromise the structural integrity of host red-blood cells. Here, Clark et al. develop a flow cytometric osmotic stability assay to show that P. vivax infection destabilizes host reticulocytes, which are less stable than P. falciparum-infected normocytes.Martha A. ClarkUsheer KanjeeGabriel W. RangelLaura CheryAnjali MascarenhasEdwin GomesPradipsinh K. RathodCarlo BrugnaraMarcelo U. FerreiraManoj T. DuraisinghNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Martha A. Clark Usheer Kanjee Gabriel W. Rangel Laura Chery Anjali Mascarenhas Edwin Gomes Pradipsinh K. Rathod Carlo Brugnara Marcelo U. Ferreira Manoj T. Duraisingh Plasmodium vivax infection compromises reticulocyte stability
description	During Plasmodium intra-erythrocytic developmental, parasites compromise the structural integrity of host red-blood cells. Here, Clark et al. develop a flow cytometric osmotic stability assay to show that P. vivax infection destabilizes host reticulocytes, which are less stable than P. falciparum-infected normocytes.
format	article
author	Martha A. Clark Usheer Kanjee Gabriel W. Rangel Laura Chery Anjali Mascarenhas Edwin Gomes Pradipsinh K. Rathod Carlo Brugnara Marcelo U. Ferreira Manoj T. Duraisingh
author_facet	Martha A. Clark Usheer Kanjee Gabriel W. Rangel Laura Chery Anjali Mascarenhas Edwin Gomes Pradipsinh K. Rathod Carlo Brugnara Marcelo U. Ferreira Manoj T. Duraisingh
author_sort	Martha A. Clark
title	Plasmodium vivax infection compromises reticulocyte stability
title_short	Plasmodium vivax infection compromises reticulocyte stability
title_full	Plasmodium vivax infection compromises reticulocyte stability
title_fullStr	Plasmodium vivax infection compromises reticulocyte stability
title_full_unstemmed	Plasmodium vivax infection compromises reticulocyte stability
title_sort	plasmodium vivax infection compromises reticulocyte stability
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/048bfeac5af7438dad7b6d45ad8104b5
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_version_	1718393311144706048

Plasmodium vivax infection compromises reticulocyte stability

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