Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation

The TATA-box binding protein (TBP) is required for transcription initiation in archaea and eukaryotes. Here the authors delineate how TBP’s function has evolved new functional features through context-dependent interactions with various protein partners.

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Detalles Bibliográficos
Autores principales: Charles N. J. Ravarani, Tilman Flock, Sreenivas Chavali, Madhanagopal Anandapadamanaban, M. Madan Babu, Santhanam Balaji
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/04a4a2d60faa49f28d7ee8556002ba1a
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Descripción
Sumario:The TATA-box binding protein (TBP) is required for transcription initiation in archaea and eukaryotes. Here the authors delineate how TBP’s function has evolved new functional features through context-dependent interactions with various protein partners.