Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation

The TATA-box binding protein (TBP) is required for transcription initiation in archaea and eukaryotes. Here the authors delineate how TBP’s function has evolved new functional features through context-dependent interactions with various protein partners.

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Autores principales: Charles N. J. Ravarani, Tilman Flock, Sreenivas Chavali, Madhanagopal Anandapadamanaban, M. Madan Babu, Santhanam Balaji
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/04a4a2d60faa49f28d7ee8556002ba1a
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spelling oai:doaj.org-article:04a4a2d60faa49f28d7ee8556002ba1a2021-12-02T16:50:30ZMolecular determinants underlying functional innovations of TBP and their impact on transcription initiation10.1038/s41467-020-16182-z2041-1723https://doaj.org/article/04a4a2d60faa49f28d7ee8556002ba1a2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16182-zhttps://doaj.org/toc/2041-1723The TATA-box binding protein (TBP) is required for transcription initiation in archaea and eukaryotes. Here the authors delineate how TBP’s function has evolved new functional features through context-dependent interactions with various protein partners.Charles N. J. RavaraniTilman FlockSreenivas ChavaliMadhanagopal AnandapadamanabanM. Madan BabuSanthanam BalajiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Charles N. J. Ravarani
Tilman Flock
Sreenivas Chavali
Madhanagopal Anandapadamanaban
M. Madan Babu
Santhanam Balaji
Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
description The TATA-box binding protein (TBP) is required for transcription initiation in archaea and eukaryotes. Here the authors delineate how TBP’s function has evolved new functional features through context-dependent interactions with various protein partners.
format article
author Charles N. J. Ravarani
Tilman Flock
Sreenivas Chavali
Madhanagopal Anandapadamanaban
M. Madan Babu
Santhanam Balaji
author_facet Charles N. J. Ravarani
Tilman Flock
Sreenivas Chavali
Madhanagopal Anandapadamanaban
M. Madan Babu
Santhanam Balaji
author_sort Charles N. J. Ravarani
title Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
title_short Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
title_full Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
title_fullStr Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
title_full_unstemmed Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
title_sort molecular determinants underlying functional innovations of tbp and their impact on transcription initiation
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/04a4a2d60faa49f28d7ee8556002ba1a
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AT madhanagopalanandapadamanaban moleculardeterminantsunderlyingfunctionalinnovationsoftbpandtheirimpactontranscriptioninitiation
AT mmadanbabu moleculardeterminantsunderlyingfunctionalinnovationsoftbpandtheirimpactontranscriptioninitiation
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