Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation

The TATA-box binding protein (TBP) is required for transcription initiation in archaea and eukaryotes. Here the authors delineate how TBP’s function has evolved new functional features through context-dependent interactions with various protein partners.

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Auteurs principaux:	Charles N. J. Ravarani, Tilman Flock, Sreenivas Chavali, Madhanagopal Anandapadamanaban, M. Madan Babu, Santhanam Balaji
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/04a4a2d60faa49f28d7ee8556002ba1a
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spelling	oai:doaj.org-article:04a4a2d60faa49f28d7ee8556002ba1a2021-12-02T16:50:30ZMolecular determinants underlying functional innovations of TBP and their impact on transcription initiation10.1038/s41467-020-16182-z2041-1723https://doaj.org/article/04a4a2d60faa49f28d7ee8556002ba1a2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16182-zhttps://doaj.org/toc/2041-1723The TATA-box binding protein (TBP) is required for transcription initiation in archaea and eukaryotes. Here the authors delineate how TBP’s function has evolved new functional features through context-dependent interactions with various protein partners.Charles N. J. RavaraniTilman FlockSreenivas ChavaliMadhanagopal AnandapadamanabanM. Madan BabuSanthanam BalajiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Charles N. J. Ravarani Tilman Flock Sreenivas Chavali Madhanagopal Anandapadamanaban M. Madan Babu Santhanam Balaji Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
description	The TATA-box binding protein (TBP) is required for transcription initiation in archaea and eukaryotes. Here the authors delineate how TBP’s function has evolved new functional features through context-dependent interactions with various protein partners.
format	article
author	Charles N. J. Ravarani Tilman Flock Sreenivas Chavali Madhanagopal Anandapadamanaban M. Madan Babu Santhanam Balaji
author_facet	Charles N. J. Ravarani Tilman Flock Sreenivas Chavali Madhanagopal Anandapadamanaban M. Madan Babu Santhanam Balaji
author_sort	Charles N. J. Ravarani
title	Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
title_short	Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
title_full	Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
title_fullStr	Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
title_full_unstemmed	Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation
title_sort	molecular determinants underlying functional innovations of tbp and their impact on transcription initiation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/04a4a2d60faa49f28d7ee8556002ba1a
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Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation

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