CD4<sup>+</sup> T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during <italic toggle="yes">Cryptococcus neoformans</italic> Meningoencephalitis
ABSTRACT Cryptococcus neoformans is a major fungal pathogen that disseminates to the central nervous system (CNS) to cause fatal meningoencephalitis, but little is known about immune responses within this immune-privileged site. CD4+ T cells have demonstrated roles in anticryptococcal defenses, but...
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Autores principales: | Lori M. Neal, Enze Xing, Jintao Xu, Jessica L. Kolbe, John J. Osterholzer, Benjamin M. Segal, Peter R. Williamson, Michal A. Olszewski |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/04a70e055741476f825df598d7cdb177 |
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