Mokko Lactone Attenuates Doxorubicin-Induced Hepatotoxicity in Rats: Emphasis on Sirt-1/FOXO1/NF-κB Axis
Doxorubicin (DOX), a common chemotherapeutic agent, suffers serious adverse effects including hepatotoxicity. Mokko lactone (ML) is a guainolide sesquiterpene with promising biological activities. The study aimed to evaluate the protection offered by ML against hepatotoxicity induced by DOX in rats....
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Auteurs principaux: | Alaa Sirwi, Rasheed A. Shaik, Abdulmohsin J. Alamoudi, Basma G. Eid, Ahmed K. Kammoun, Sabrin R. M. Ibrahim, Gamal A. Mohamed, Hossam M. Abdallah, Ashraf B. Abdel-Naim |
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Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
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Sujets: | |
Accès en ligne: | https://doaj.org/article/04abce26c7904fd6ac4f97af8bc98c5c |
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