Cell barrier function of resident peritoneal macrophages in post-operative adhesions

Peritoneal adhesions are a major cause of complications after abdominal surgery. Here the authors use a post-operative abdominal adhesion model in mice to show that resident F4/80HighCD206− macrophages form a protective barrier that can be enhanced by IL-4 administration or adoptive transfer of thes...

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Autores principales: Tomoya Ito, Yusuke Shintani, Laura Fields, Manabu Shiraishi, Mihai‑Nicolae Podaru, Satoshi Kainuma, Kizuku Yamashita, Kazuya Kobayashi, Mauro Perretti, Fiona Lewis-McDougall, Ken Suzuki
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/04b291aa73f1460e9d361ec21581a4ce
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spelling oai:doaj.org-article:04b291aa73f1460e9d361ec21581a4ce2021-12-02T15:51:07ZCell barrier function of resident peritoneal macrophages in post-operative adhesions10.1038/s41467-021-22536-y2041-1723https://doaj.org/article/04b291aa73f1460e9d361ec21581a4ce2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22536-yhttps://doaj.org/toc/2041-1723Peritoneal adhesions are a major cause of complications after abdominal surgery. Here the authors use a post-operative abdominal adhesion model in mice to show that resident F4/80HighCD206− macrophages form a protective barrier that can be enhanced by IL-4 administration or adoptive transfer of these cells.Tomoya ItoYusuke ShintaniLaura FieldsManabu ShiraishiMihai‑Nicolae PodaruSatoshi KainumaKizuku YamashitaKazuya KobayashiMauro PerrettiFiona Lewis-McDougallKen SuzukiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tomoya Ito
Yusuke Shintani
Laura Fields
Manabu Shiraishi
Mihai‑Nicolae Podaru
Satoshi Kainuma
Kizuku Yamashita
Kazuya Kobayashi
Mauro Perretti
Fiona Lewis-McDougall
Ken Suzuki
Cell barrier function of resident peritoneal macrophages in post-operative adhesions
description Peritoneal adhesions are a major cause of complications after abdominal surgery. Here the authors use a post-operative abdominal adhesion model in mice to show that resident F4/80HighCD206− macrophages form a protective barrier that can be enhanced by IL-4 administration or adoptive transfer of these cells.
format article
author Tomoya Ito
Yusuke Shintani
Laura Fields
Manabu Shiraishi
Mihai‑Nicolae Podaru
Satoshi Kainuma
Kizuku Yamashita
Kazuya Kobayashi
Mauro Perretti
Fiona Lewis-McDougall
Ken Suzuki
author_facet Tomoya Ito
Yusuke Shintani
Laura Fields
Manabu Shiraishi
Mihai‑Nicolae Podaru
Satoshi Kainuma
Kizuku Yamashita
Kazuya Kobayashi
Mauro Perretti
Fiona Lewis-McDougall
Ken Suzuki
author_sort Tomoya Ito
title Cell barrier function of resident peritoneal macrophages in post-operative adhesions
title_short Cell barrier function of resident peritoneal macrophages in post-operative adhesions
title_full Cell barrier function of resident peritoneal macrophages in post-operative adhesions
title_fullStr Cell barrier function of resident peritoneal macrophages in post-operative adhesions
title_full_unstemmed Cell barrier function of resident peritoneal macrophages in post-operative adhesions
title_sort cell barrier function of resident peritoneal macrophages in post-operative adhesions
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/04b291aa73f1460e9d361ec21581a4ce
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