Lung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia

Lung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia

Abstract To assess the usefulness of lung ultrasound (LUS) for identifying community-acquired pneumonia (CAP) among adult patients with suspected lower respiratory tract infection (LRTI) and for discriminating between CAP with different cultural statuses, etiologies, and outcomes. LUS was performed...

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Autores principales: Filippo Mearelli, Chiara Casarsa, Alessandro Trapani, Pierlanfranco D’agaro, Cristina Moras, Francesca Spagnol, Federica Pellicori, Alessio Nunnari, Alice Massolin, Giulia Barbati, Gianni Biolo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/04b7683a55804ff5bb955a2d976aef6c
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spelling oai:doaj.org-article:04b7683a55804ff5bb955a2d976aef6c2021-12-02T19:02:33ZLung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia10.1038/s41598-021-96380-x2045-2322https://doaj.org/article/04b7683a55804ff5bb955a2d976aef6c2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-96380-xhttps://doaj.org/toc/2045-2322Abstract To assess the usefulness of lung ultrasound (LUS) for identifying community-acquired pneumonia (CAP) among adult patients with suspected lower respiratory tract infection (LRTI) and for discriminating between CAP with different cultural statuses, etiologies, and outcomes. LUS was performed at internal medicine ward admission. The performance of chest X-ray (CXR) and LUS in diagnosing CAP in 410 patients with suspected LRTI was determined. All possible positive results for pneumonia on LUS were condensed into pattern 1 (consolidation + / − alveolar-interstitial syndrome) and pattern 2 (alveolar-interstitial syndrome). The performance of LUS in predicting culture-positive status, bacterial etiology, and adverse outcomes of CAP was assessed in 315 patients. The area under the receiver operating characteristic curve for diagnosing CAP by LUS was significantly higher than for diagnosis CAP by CXR (0.93 and 0.71, respectively; p < 0.001). Pattern 1 predicted CAP with bacterial and mixed bacterial and viral etiologies with positive predictive values of 99% (95% CI, 94–100%) and 97% (95% CI, 81–99%), respectively. Pattern 2 ruled out mortality with a negative predictive value of 95% (95% CI, 86–98%), respectively. In this study, LUS was useful in predicting a diagnosis of CAP, the bacterial etiology of CAP, and favorable outcome in patients with CAP.Filippo MearelliChiara CasarsaAlessandro TrapaniPierlanfranco D’agaroCristina MorasFrancesca SpagnolFederica PellicoriAlessio NunnariAlice MassolinGiulia BarbatiGianni BioloNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Filippo Mearelli
Chiara Casarsa
Alessandro Trapani
Pierlanfranco D’agaro
Cristina Moras
Francesca Spagnol
Federica Pellicori
Alessio Nunnari
Alice Massolin
Giulia Barbati
Gianni Biolo
Lung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia
description Abstract To assess the usefulness of lung ultrasound (LUS) for identifying community-acquired pneumonia (CAP) among adult patients with suspected lower respiratory tract infection (LRTI) and for discriminating between CAP with different cultural statuses, etiologies, and outcomes. LUS was performed at internal medicine ward admission. The performance of chest X-ray (CXR) and LUS in diagnosing CAP in 410 patients with suspected LRTI was determined. All possible positive results for pneumonia on LUS were condensed into pattern 1 (consolidation + / − alveolar-interstitial syndrome) and pattern 2 (alveolar-interstitial syndrome). The performance of LUS in predicting culture-positive status, bacterial etiology, and adverse outcomes of CAP was assessed in 315 patients. The area under the receiver operating characteristic curve for diagnosing CAP by LUS was significantly higher than for diagnosis CAP by CXR (0.93 and 0.71, respectively; p < 0.001). Pattern 1 predicted CAP with bacterial and mixed bacterial and viral etiologies with positive predictive values of 99% (95% CI, 94–100%) and 97% (95% CI, 81–99%), respectively. Pattern 2 ruled out mortality with a negative predictive value of 95% (95% CI, 86–98%), respectively. In this study, LUS was useful in predicting a diagnosis of CAP, the bacterial etiology of CAP, and favorable outcome in patients with CAP.
format article
author Filippo Mearelli
Chiara Casarsa
Alessandro Trapani
Pierlanfranco D’agaro
Cristina Moras
Francesca Spagnol
Federica Pellicori
Alessio Nunnari
Alice Massolin
Giulia Barbati
Gianni Biolo
author_facet Filippo Mearelli
Chiara Casarsa
Alessandro Trapani
Pierlanfranco D’agaro
Cristina Moras
Francesca Spagnol
Federica Pellicori
Alessio Nunnari
Alice Massolin
Giulia Barbati
Gianni Biolo
author_sort Filippo Mearelli
title Lung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia
title_short Lung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia
title_full Lung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia
title_fullStr Lung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia
title_full_unstemmed Lung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia
title_sort lung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/04b7683a55804ff5bb955a2d976aef6c
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