ILDR2 stabilization is regulated by its interaction with GRP78

Abstract Ildr2 was initially identified as a genetic modifier of diabetes susceptibility in B6.DBA Lep ob  congenic mice, and was associated with decreased β-cell replication rates, reduced β-cell mass, and persistent mild hypoinsulinemic hyperglycemia. However, the molecular mechanisms of how the I...

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Autores principales: Kazuhisa Watanabe, Kazuhiro Nakayama, Satoshi Ohta, Ayumi Matsumoto, Hidetoshi Tsuda, Sadahiko Iwamoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/04dd66a84d6c4d78bf181fad4c433081
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