Synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents

In examining for unique insecticidal agents, two derivatives namely, 2-((3-cyano-4,6-distyrylpyridin-2-yl)thio)-N-(4-nitrophenyl)acetamide (2) and 3-amino-N-(4-nitrophenyl)-4,6-distyrylthieno[2,3-b]pyridine-2-carboxamide (3) were synthesized from distyrylpyridine-2-thione (1). The new compo...

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Autores principales:	Shaban A. A. Abdel-Raheem, Adel M. Kamal El-Dean, Mokhtar A. Abd ul-Malik, Reda Hassanien, Mohamed E. A. El-Sayed, Aly A. Abd-Ella, Sameh A. Zawam, Mahmoud S. Tolba
Formato:	article
Lenguaje:	EN
Publicado:	Growing Science 2022
Materias:	Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/04ddd916f02240a1a2fec399410e61c6
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spelling	oai:doaj.org-article:04ddd916f02240a1a2fec399410e61c62021-11-12T12:52:42ZSynthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents1927-72961927-730X10.5267/j.ccl.2021.10.001https://doaj.org/article/04ddd916f02240a1a2fec399410e61c62022-01-01T00:00:00Zhttp://www.growingscience.com/ccl/Vol11/ccl_2021_39.pdfhttps://doaj.org/toc/1927-7296https://doaj.org/toc/1927-730X In examining for unique insecticidal agents, two derivatives namely, 2-((3-cyano-4,6-distyrylpyridin-2-yl)thio)-N-(4-nitrophenyl)acetamide (2) and 3-amino-N-(4-nitrophenyl)-4,6-distyrylthieno[2,3-b]pyridine-2-carboxamide (3) were synthesized from distyrylpyridine-2-thione (1). The new compounds were structurally clarified by spectral and elemental analysis data. The insecticidal activity of these compounds were carried out against cowpea aphid, Aphis craccivora Koch. It is demonstrated that the compounds 2 and 3 have noteworthy insecticidal activity against nymphs of cowpea aphid with LC50 values of 0.025-0.027 ppm and 0.005-0.006 ppm after 24 h and 48 h of treatment, respectively. Also, the compounds 2 and 3 have noteworthy insecticidal activity against adults of cowpea aphid with LC50 values of 0.112-0.129 ppm and 0.014-0.015 ppm after 24 h and 48 h of treatment, respectively, that were comparable to that of the control acetamiprid.Shaban A. A. Abdel-RaheemAdel M. Kamal El-DeanMokhtar A. Abd ul-MalikReda HassanienMohamed E. A. El-SayedAly A. Abd-EllaSameh A. ZawamMahmoud S. TolbaGrowing SciencearticleChemistryQD1-999ENCurrent Chemistry Letters, Vol 11, Iss 1, Pp 23-28 (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Chemistry QD1-999
spellingShingle	Chemistry QD1-999 Shaban A. A. Abdel-Raheem Adel M. Kamal El-Dean Mokhtar A. Abd ul-Malik Reda Hassanien Mohamed E. A. El-Sayed Aly A. Abd-Ella Sameh A. Zawam Mahmoud S. Tolba Synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents
description	In examining for unique insecticidal agents, two derivatives namely, 2-((3-cyano-4,6-distyrylpyridin-2-yl)thio)-N-(4-nitrophenyl)acetamide (2) and 3-amino-N-(4-nitrophenyl)-4,6-distyrylthieno[2,3-b]pyridine-2-carboxamide (3) were synthesized from distyrylpyridine-2-thione (1). The new compounds were structurally clarified by spectral and elemental analysis data. The insecticidal activity of these compounds were carried out against cowpea aphid, Aphis craccivora Koch. It is demonstrated that the compounds 2 and 3 have noteworthy insecticidal activity against nymphs of cowpea aphid with LC50 values of 0.025-0.027 ppm and 0.005-0.006 ppm after 24 h and 48 h of treatment, respectively. Also, the compounds 2 and 3 have noteworthy insecticidal activity against adults of cowpea aphid with LC50 values of 0.112-0.129 ppm and 0.014-0.015 ppm after 24 h and 48 h of treatment, respectively, that were comparable to that of the control acetamiprid.
format	article
author	Shaban A. A. Abdel-Raheem Adel M. Kamal El-Dean Mokhtar A. Abd ul-Malik Reda Hassanien Mohamed E. A. El-Sayed Aly A. Abd-Ella Sameh A. Zawam Mahmoud S. Tolba
author_facet	Shaban A. A. Abdel-Raheem Adel M. Kamal El-Dean Mokhtar A. Abd ul-Malik Reda Hassanien Mohamed E. A. El-Sayed Aly A. Abd-Ella Sameh A. Zawam Mahmoud S. Tolba
author_sort	Shaban A. A. Abdel-Raheem
title	Synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents
title_short	Synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents
title_full	Synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents
title_fullStr	Synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents
title_full_unstemmed	Synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents
title_sort	synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents
publisher	Growing Science
publishDate	2022
url	https://doaj.org/article/04ddd916f02240a1a2fec399410e61c6
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Synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents

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