Diagnostic Approach to Patients with Stable Angina and No Obstructive Coronary Arteries

The diagnosis of microvascular angina (MVA) is usually considered in patients presenting with angina symptoms and evidence of MI on non-invasive stress tests but normal coronary arteries at angiography. A definitive diagnosis of MVA, however, would require the presence of coronary microvascular dysf...

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Autor principal: Gaetano Antonio Lanza
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Lenguaje:EN
Publicado: Radcliffe Medical Media 2019
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Acceso en línea:https://doaj.org/article/04df34ea5bfc467c804f6cf1ba879a26
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spelling oai:doaj.org-article:04df34ea5bfc467c804f6cf1ba879a262021-12-04T16:01:40ZDiagnostic Approach to Patients with Stable Angina and No Obstructive Coronary Arteries10.15420/ecr.2019.22.21758-37641758-3756https://doaj.org/article/04df34ea5bfc467c804f6cf1ba879a262019-07-01T00:00:00Zhttps://www.ecrjournal.com/articles/Stable-Angina-No-Obstructive-Coronary-Arterieshttps://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764The diagnosis of microvascular angina (MVA) is usually considered in patients presenting with angina symptoms and evidence of MI on non-invasive stress tests but normal coronary arteries at angiography. A definitive diagnosis of MVA, however, would require the presence of coronary microvascular dysfunction. Several invasive (e.g. intracoronary Doppler wire recording and thermodilution) and non-invasive (e.g. PET, cardiac MRI, transthoracic Doppler echocardiography) methods can be applied to obtain a diagnosis. Both endothelium- dependent and -independent coronary microvascular dilator function, as well as increased microvascular constrictor activity, should be investigated. The main issues in the assessment of clinical and diagnostic findings in patients with suspected MVA are discussed and a diagnostic approach is suggested.Gaetano Antonio LanzaRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 14, Iss 2, Pp 97-102 (2019)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Gaetano Antonio Lanza
Diagnostic Approach to Patients with Stable Angina and No Obstructive Coronary Arteries
description The diagnosis of microvascular angina (MVA) is usually considered in patients presenting with angina symptoms and evidence of MI on non-invasive stress tests but normal coronary arteries at angiography. A definitive diagnosis of MVA, however, would require the presence of coronary microvascular dysfunction. Several invasive (e.g. intracoronary Doppler wire recording and thermodilution) and non-invasive (e.g. PET, cardiac MRI, transthoracic Doppler echocardiography) methods can be applied to obtain a diagnosis. Both endothelium- dependent and -independent coronary microvascular dilator function, as well as increased microvascular constrictor activity, should be investigated. The main issues in the assessment of clinical and diagnostic findings in patients with suspected MVA are discussed and a diagnostic approach is suggested.
format article
author Gaetano Antonio Lanza
author_facet Gaetano Antonio Lanza
author_sort Gaetano Antonio Lanza
title Diagnostic Approach to Patients with Stable Angina and No Obstructive Coronary Arteries
title_short Diagnostic Approach to Patients with Stable Angina and No Obstructive Coronary Arteries
title_full Diagnostic Approach to Patients with Stable Angina and No Obstructive Coronary Arteries
title_fullStr Diagnostic Approach to Patients with Stable Angina and No Obstructive Coronary Arteries
title_full_unstemmed Diagnostic Approach to Patients with Stable Angina and No Obstructive Coronary Arteries
title_sort diagnostic approach to patients with stable angina and no obstructive coronary arteries
publisher Radcliffe Medical Media
publishDate 2019
url https://doaj.org/article/04df34ea5bfc467c804f6cf1ba879a26
work_keys_str_mv AT gaetanoantoniolanza diagnosticapproachtopatientswithstableanginaandnoobstructivecoronaryarteries
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