Neutron reflectometry and NMR spectroscopy of full-length Bcl-2 protein reveal its membrane localization and conformation

Through neutron reflectometry and NMR spectroscopy studies, Mushtaq et al study the full-length Bcl-2 protein reconstituted in lipid bilayers. They find that, in contrast to previously studied truncated, soluble protein versions, intact Bcl-2 is mainly embedded in the membrane with its regulatory lo...

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Autores principales: Ameeq Ul Mushtaq, Jörgen Ådén, Luke A. Clifton, Hanna Wacklin-Knecht, Mario Campana, Artur P. G. Dingeldein, Cecilia Persson, Tobias Sparrman, Gerhard Gröbner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/04e38e0553dd4095833d3e485d2fc850
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