Complement Factor H-Related 3 Enhanced Inflammation and Complement Activation in Human RPE Cells

Complement Factor H-Related 3 (FHR-3) is a major regulator of the complement system, which is associated with different diseases, such as age-related macular degeneration (AMD). However, the non-canonical local, cellular functions of FHR-3 remained poorly understood. Here, we report that FHR-3 bound...

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Bibliographic Details
Main Authors: Nicole Schäfer, Anas Rasras, Delia M. Ormenisan, Sabine Amslinger, Volker Enzmann, Herbert Jägle, Diana Pauly
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
AMD
Online Access:https://doaj.org/article/04e4a6fe38e44a64a7d7be9d64f821b8
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