AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

Glioblastomas (GBMs) are highly invasive brain tumours, but the underlying mechanisms of GBM invasion are unclear. Here, the authors perform an RNA interference screen and identify AN1-Type Zinc Finger protein 3 (ZFAND3) as a regulator of GBM invasion, and find that it acts through the transcription...

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Autores principales:	Anne Schuster, Eliane Klein, Virginie Neirinckx, Arnon Møldrup Knudsen, Carina Fabian, Ann-Christin Hau, Monika Dieterle, Anais Oudin, Petr V. Nazarov, Anna Golebiewska, Arnaud Muller, Daniel Perez-Hernandez, Sophie Rodius, Gunnar Dittmar, Rolf Bjerkvig, Christel Herold-Mende, Barbara Klink, Bjarne Winther Kristensen, Simone P. Niclou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/04ea0e869f414c02aaa7957879d7374d
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spelling	oai:doaj.org-article:04ea0e869f414c02aaa7957879d7374d2021-12-02T13:57:55ZAN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion10.1038/s41467-020-20029-y2041-1723https://doaj.org/article/04ea0e869f414c02aaa7957879d7374d2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20029-yhttps://doaj.org/toc/2041-1723Glioblastomas (GBMs) are highly invasive brain tumours, but the underlying mechanisms of GBM invasion are unclear. Here, the authors perform an RNA interference screen and identify AN1-Type Zinc Finger protein 3 (ZFAND3) as a regulator of GBM invasion, and find that it acts through the transcriptional regulation of invasion-related genes.Anne SchusterEliane KleinVirginie NeirinckxArnon Møldrup KnudsenCarina FabianAnn-Christin HauMonika DieterleAnais OudinPetr V. NazarovAnna GolebiewskaArnaud MullerDaniel Perez-HernandezSophie RodiusGunnar DittmarRolf BjerkvigChristel Herold-MendeBarbara KlinkBjarne Winther KristensenSimone P. NiclouNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anne Schuster Eliane Klein Virginie Neirinckx Arnon Møldrup Knudsen Carina Fabian Ann-Christin Hau Monika Dieterle Anais Oudin Petr V. Nazarov Anna Golebiewska Arnaud Muller Daniel Perez-Hernandez Sophie Rodius Gunnar Dittmar Rolf Bjerkvig Christel Herold-Mende Barbara Klink Bjarne Winther Kristensen Simone P. Niclou AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion
description	Glioblastomas (GBMs) are highly invasive brain tumours, but the underlying mechanisms of GBM invasion are unclear. Here, the authors perform an RNA interference screen and identify AN1-Type Zinc Finger protein 3 (ZFAND3) as a regulator of GBM invasion, and find that it acts through the transcriptional regulation of invasion-related genes.
format	article
author	Anne Schuster Eliane Klein Virginie Neirinckx Arnon Møldrup Knudsen Carina Fabian Ann-Christin Hau Monika Dieterle Anais Oudin Petr V. Nazarov Anna Golebiewska Arnaud Muller Daniel Perez-Hernandez Sophie Rodius Gunnar Dittmar Rolf Bjerkvig Christel Herold-Mende Barbara Klink Bjarne Winther Kristensen Simone P. Niclou
author_facet	Anne Schuster Eliane Klein Virginie Neirinckx Arnon Møldrup Knudsen Carina Fabian Ann-Christin Hau Monika Dieterle Anais Oudin Petr V. Nazarov Anna Golebiewska Arnaud Muller Daniel Perez-Hernandez Sophie Rodius Gunnar Dittmar Rolf Bjerkvig Christel Herold-Mende Barbara Klink Bjarne Winther Kristensen Simone P. Niclou
author_sort	Anne Schuster
title	AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion
title_short	AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion
title_full	AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion
title_fullStr	AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion
title_full_unstemmed	AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion
title_sort	an1-type zinc finger protein 3 (zfand3) is a transcriptional regulator that drives glioblastoma invasion
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/04ea0e869f414c02aaa7957879d7374d
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AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

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