A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

Zika virus infection can result in congenital disorders and cause disease in adults, and there is currently no approved vaccine. Here Shan et al. show that a single dose of a live-attenuated Zika vaccine prevents infection, testis damage and transmission to the fetus during pregnancy in different an...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Chao Shan, Antonio E. Muruato, Brett W. Jagger, Justin Richner, Bruno T. D. Nunes, Daniele B. A. Medeiros, Xuping Xie, Jannyce G. C. Nunes, Kaitlyn M. Morabito, Wing-Pui Kong, Theodore C. Pierson, Alan D. Barrett, Scott C. Weaver, Shannan L. Rossi, Pedro F. C. Vasconcelos, Barney S. Graham, Michael S. Diamond, Pei-Yong Shi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/04efca35dcf0457db06e055dcc33fee4
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Zika virus infection can result in congenital disorders and cause disease in adults, and there is currently no approved vaccine. Here Shan et al. show that a single dose of a live-attenuated Zika vaccine prevents infection, testis damage and transmission to the fetus during pregnancy in different animal models.

Ejemplares similares