A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

Zika virus infection can result in congenital disorders and cause disease in adults, and there is currently no approved vaccine. Here Shan et al. show that a single dose of a live-attenuated Zika vaccine prevents infection, testis damage and transmission to the fetus during pregnancy in different an...

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Autores principales: Chao Shan, Antonio E. Muruato, Brett W. Jagger, Justin Richner, Bruno T. D. Nunes, Daniele B. A. Medeiros, Xuping Xie, Jannyce G. C. Nunes, Kaitlyn M. Morabito, Wing-Pui Kong, Theodore C. Pierson, Alan D. Barrett, Scott C. Weaver, Shannan L. Rossi, Pedro F. C. Vasconcelos, Barney S. Graham, Michael S. Diamond, Pei-Yong Shi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/04efca35dcf0457db06e055dcc33fee4
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spelling oai:doaj.org-article:04efca35dcf0457db06e055dcc33fee42021-12-02T14:42:04ZA single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage10.1038/s41467-017-00737-82041-1723https://doaj.org/article/04efca35dcf0457db06e055dcc33fee42017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00737-8https://doaj.org/toc/2041-1723Zika virus infection can result in congenital disorders and cause disease in adults, and there is currently no approved vaccine. Here Shan et al. show that a single dose of a live-attenuated Zika vaccine prevents infection, testis damage and transmission to the fetus during pregnancy in different animal models.Chao ShanAntonio E. MuruatoBrett W. JaggerJustin RichnerBruno T. D. NunesDaniele B. A. MedeirosXuping XieJannyce G. C. NunesKaitlyn M. MorabitoWing-Pui KongTheodore C. PiersonAlan D. BarrettScott C. WeaverShannan L. RossiPedro F. C. VasconcelosBarney S. GrahamMichael S. DiamondPei-Yong ShiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chao Shan
Antonio E. Muruato
Brett W. Jagger
Justin Richner
Bruno T. D. Nunes
Daniele B. A. Medeiros
Xuping Xie
Jannyce G. C. Nunes
Kaitlyn M. Morabito
Wing-Pui Kong
Theodore C. Pierson
Alan D. Barrett
Scott C. Weaver
Shannan L. Rossi
Pedro F. C. Vasconcelos
Barney S. Graham
Michael S. Diamond
Pei-Yong Shi
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
description Zika virus infection can result in congenital disorders and cause disease in adults, and there is currently no approved vaccine. Here Shan et al. show that a single dose of a live-attenuated Zika vaccine prevents infection, testis damage and transmission to the fetus during pregnancy in different animal models.
format article
author Chao Shan
Antonio E. Muruato
Brett W. Jagger
Justin Richner
Bruno T. D. Nunes
Daniele B. A. Medeiros
Xuping Xie
Jannyce G. C. Nunes
Kaitlyn M. Morabito
Wing-Pui Kong
Theodore C. Pierson
Alan D. Barrett
Scott C. Weaver
Shannan L. Rossi
Pedro F. C. Vasconcelos
Barney S. Graham
Michael S. Diamond
Pei-Yong Shi
author_facet Chao Shan
Antonio E. Muruato
Brett W. Jagger
Justin Richner
Bruno T. D. Nunes
Daniele B. A. Medeiros
Xuping Xie
Jannyce G. C. Nunes
Kaitlyn M. Morabito
Wing-Pui Kong
Theodore C. Pierson
Alan D. Barrett
Scott C. Weaver
Shannan L. Rossi
Pedro F. C. Vasconcelos
Barney S. Graham
Michael S. Diamond
Pei-Yong Shi
author_sort Chao Shan
title A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
title_short A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
title_full A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
title_fullStr A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
title_full_unstemmed A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
title_sort single-dose live-attenuated vaccine prevents zika virus pregnancy transmission and testis damage
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/04efca35dcf0457db06e055dcc33fee4
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