Tau is required for the function of extrasynaptic NMDA receptors
Abstract Tau is a microtubule-associated neuronal protein found mainly in axons. However, increasing evidence indicates that it is also present in dendrites, where it serves as an essential mediator of synaptic NMDA (N-methyl-D-aspartate) receptor-dependent excitotoxicity. Of note, NMDA receptors ca...
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Autores principales: | Noemí Pallas-Bazarra, Jonathan Draffin, Raquel Cuadros, José Antonio Esteban, Jesús Avila |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/04fb84d008734a7297c19f3d82650bb8 |
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