Self-organized centripetal movement of corneal epithelium in the absence of external cues
The cornea is formed of cells that originate from the outer circle of stem cells and that move towards its centre. Here, the authors show that the movement pattern is self-organised, requiring no cues, and that stem cell leakage may account for the presence of stem cells at the centre of the cornea.
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Nature Portfolio
2016
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oai:doaj.org-article:04fc9e7c6a03492b87b0a77094cdb6422021-12-02T17:31:47ZSelf-organized centripetal movement of corneal epithelium in the absence of external cues10.1038/ncomms123882041-1723https://doaj.org/article/04fc9e7c6a03492b87b0a77094cdb6422016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12388https://doaj.org/toc/2041-1723The cornea is formed of cells that originate from the outer circle of stem cells and that move towards its centre. Here, the authors show that the movement pattern is self-organised, requiring no cues, and that stem cell leakage may account for the presence of stem cells at the centre of the cornea.Erwin P. LoboNaomi C. DelicAlex RichardsonVanisri RavirajGary M. HallidayNick Di GirolamoMary R. MyerscoughJ. Guy LyonsNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
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Science Q Erwin P. Lobo Naomi C. Delic Alex Richardson Vanisri Raviraj Gary M. Halliday Nick Di Girolamo Mary R. Myerscough J. Guy Lyons Self-organized centripetal movement of corneal epithelium in the absence of external cues |
description |
The cornea is formed of cells that originate from the outer circle of stem cells and that move towards its centre. Here, the authors show that the movement pattern is self-organised, requiring no cues, and that stem cell leakage may account for the presence of stem cells at the centre of the cornea. |
format |
article |
author |
Erwin P. Lobo Naomi C. Delic Alex Richardson Vanisri Raviraj Gary M. Halliday Nick Di Girolamo Mary R. Myerscough J. Guy Lyons |
author_facet |
Erwin P. Lobo Naomi C. Delic Alex Richardson Vanisri Raviraj Gary M. Halliday Nick Di Girolamo Mary R. Myerscough J. Guy Lyons |
author_sort |
Erwin P. Lobo |
title |
Self-organized centripetal movement of corneal epithelium in the absence of external cues |
title_short |
Self-organized centripetal movement of corneal epithelium in the absence of external cues |
title_full |
Self-organized centripetal movement of corneal epithelium in the absence of external cues |
title_fullStr |
Self-organized centripetal movement of corneal epithelium in the absence of external cues |
title_full_unstemmed |
Self-organized centripetal movement of corneal epithelium in the absence of external cues |
title_sort |
self-organized centripetal movement of corneal epithelium in the absence of external cues |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/04fc9e7c6a03492b87b0a77094cdb642 |
work_keys_str_mv |
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1718380471142842368 |