Self-organized centripetal movement of corneal epithelium in the absence of external cues

The cornea is formed of cells that originate from the outer circle of stem cells and that move towards its centre. Here, the authors show that the movement pattern is self-organised, requiring no cues, and that stem cell leakage may account for the presence of stem cells at the centre of the cornea.

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Autores principales: Erwin P. Lobo, Naomi C. Delic, Alex Richardson, Vanisri Raviraj, Gary M. Halliday, Nick Di Girolamo, Mary R. Myerscough, J. Guy Lyons
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/04fc9e7c6a03492b87b0a77094cdb642
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spelling oai:doaj.org-article:04fc9e7c6a03492b87b0a77094cdb6422021-12-02T17:31:47ZSelf-organized centripetal movement of corneal epithelium in the absence of external cues10.1038/ncomms123882041-1723https://doaj.org/article/04fc9e7c6a03492b87b0a77094cdb6422016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12388https://doaj.org/toc/2041-1723The cornea is formed of cells that originate from the outer circle of stem cells and that move towards its centre. Here, the authors show that the movement pattern is self-organised, requiring no cues, and that stem cell leakage may account for the presence of stem cells at the centre of the cornea.Erwin P. LoboNaomi C. DelicAlex RichardsonVanisri RavirajGary M. HallidayNick Di GirolamoMary R. MyerscoughJ. Guy LyonsNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Erwin P. Lobo
Naomi C. Delic
Alex Richardson
Vanisri Raviraj
Gary M. Halliday
Nick Di Girolamo
Mary R. Myerscough
J. Guy Lyons
Self-organized centripetal movement of corneal epithelium in the absence of external cues
description The cornea is formed of cells that originate from the outer circle of stem cells and that move towards its centre. Here, the authors show that the movement pattern is self-organised, requiring no cues, and that stem cell leakage may account for the presence of stem cells at the centre of the cornea.
format article
author Erwin P. Lobo
Naomi C. Delic
Alex Richardson
Vanisri Raviraj
Gary M. Halliday
Nick Di Girolamo
Mary R. Myerscough
J. Guy Lyons
author_facet Erwin P. Lobo
Naomi C. Delic
Alex Richardson
Vanisri Raviraj
Gary M. Halliday
Nick Di Girolamo
Mary R. Myerscough
J. Guy Lyons
author_sort Erwin P. Lobo
title Self-organized centripetal movement of corneal epithelium in the absence of external cues
title_short Self-organized centripetal movement of corneal epithelium in the absence of external cues
title_full Self-organized centripetal movement of corneal epithelium in the absence of external cues
title_fullStr Self-organized centripetal movement of corneal epithelium in the absence of external cues
title_full_unstemmed Self-organized centripetal movement of corneal epithelium in the absence of external cues
title_sort self-organized centripetal movement of corneal epithelium in the absence of external cues
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/04fc9e7c6a03492b87b0a77094cdb642
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