Isosteviol has beneficial effects on palmitate-induced α-cell dysfunction and gene expression.
<h4>Background</h4>Long-term exposure to high levels of fatty acids impairs insulin secretion and exaggerates glucagon secretion. The aim of this study was to explore if the antihyperglycemic agent, Isosteviol (ISV), is able to counteract palmitate-induced α-cell dysfunction and to influ...
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Main Authors: | Xiaoping Chen, Kjeld Hermansen, Jianzhong Xiao, Sara Kjaergaard Bystrup, Lorraine O'Driscoll, Per Bendix Jeppesen |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/04ff8e8e8b83477f8e67e75ef66dd43d |
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