Diurnal preference and depressive symptomatology: a meta-analysis

Abstract Eveningness, a preference for later sleep and rise times, has been associated with a number of negative outcomes in terms of both physical and mental health. A large body of evidence links eveningness to Major Depressive Disorder (MDD). However, to date, evidence quantifying this associatio...

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Autor principal: Ray Norbury
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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spelling oai:doaj.org-article:050e777c6afe42fbbf122952fd3e37352021-12-02T17:52:13ZDiurnal preference and depressive symptomatology: a meta-analysis10.1038/s41598-021-91205-32045-2322https://doaj.org/article/050e777c6afe42fbbf122952fd3e37352021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-91205-3https://doaj.org/toc/2045-2322Abstract Eveningness, a preference for later sleep and rise times, has been associated with a number of negative outcomes in terms of both physical and mental health. A large body of evidence links eveningness to Major Depressive Disorder (MDD). However, to date, evidence quantifying this association is limited. The current meta-analysis included 43 effect sizes from a total 27,996 participants. Using a random-effects model it was demonstrated that eveningness is associated with a small effect size (Fisher’s Z = − 2.4, 95% CI [− 0.27. − 0.21], p < 0.001). Substantial heterogeneity between studies was observed, with meta-regression analyses demonstrating a significant effect of mean age on the association between diurnal preference and depression. There was also evidence of potential publication bias as assessed by visual inspection of funnel plots and Egger’s test. The association between diurnal preference and depression is small in magnitude and heterogenous. A better understanding of the mechanistic underpinnings linking diurnal preference to depression and suitably powered prospective studies that allow causal inference are required.Ray NorburyNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Ray Norbury
Diurnal preference and depressive symptomatology: a meta-analysis
description Abstract Eveningness, a preference for later sleep and rise times, has been associated with a number of negative outcomes in terms of both physical and mental health. A large body of evidence links eveningness to Major Depressive Disorder (MDD). However, to date, evidence quantifying this association is limited. The current meta-analysis included 43 effect sizes from a total 27,996 participants. Using a random-effects model it was demonstrated that eveningness is associated with a small effect size (Fisher’s Z = − 2.4, 95% CI [− 0.27. − 0.21], p < 0.001). Substantial heterogeneity between studies was observed, with meta-regression analyses demonstrating a significant effect of mean age on the association between diurnal preference and depression. There was also evidence of potential publication bias as assessed by visual inspection of funnel plots and Egger’s test. The association between diurnal preference and depression is small in magnitude and heterogenous. A better understanding of the mechanistic underpinnings linking diurnal preference to depression and suitably powered prospective studies that allow causal inference are required.
format article
author Ray Norbury
author_facet Ray Norbury
author_sort Ray Norbury
title Diurnal preference and depressive symptomatology: a meta-analysis
title_short Diurnal preference and depressive symptomatology: a meta-analysis
title_full Diurnal preference and depressive symptomatology: a meta-analysis
title_fullStr Diurnal preference and depressive symptomatology: a meta-analysis
title_full_unstemmed Diurnal preference and depressive symptomatology: a meta-analysis
title_sort diurnal preference and depressive symptomatology: a meta-analysis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/050e777c6afe42fbbf122952fd3e3735
work_keys_str_mv AT raynorbury diurnalpreferenceanddepressivesymptomatologyametaanalysis
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