RB1CC1 activates RB1 pathway and inhibits proliferation and cologenic survival in human cancer.

RB1CC1 activates RB1 pathway and inhibits proliferation and cologenic survival in human cancer.

RB1-inducible coiled-coil 1 (RB1CC1, also known as FIP200) plays a role in the enhancement of the RB1 pathway through the direct binding to a GC-rich region 201bp upstream (from the initiation ATG) of the RB1 promoter. Here, we identified hSNF5 and p53 as the binding partners of RB1CC1 by immunoprec...

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Main Authors: Tokuhiro Chano, Kaichiro Ikebuchi, Yasuko Ochi, Hitosuke Tameno, Yasuhiko Tomita, Yufen Jin, Hideo Inaji, Makoto Ishitobi, Koji Teramoto, Ichiro Nishimura, Kahori Minami, Hirokazu Inoue, Takahiro Isono, Masao Saitoh, Taketoshi Shimada, Yasuo Hisa, Hidetoshi Okabe
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/05129a21b0584f3c8421d519a11d14ce
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https://doaj.org/article/05129a21b0584f3c8421d519a11d14ce

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