Etiological causes of pancytopenia: A report of 137 cases

Objective: The aim of this study is to evaluate the etiological causes of pancytopenia in patients who were admitted to the hematology ward due to pancytopenia. Materials and Methods: All patients who were admitted to the hematology ward of Ministry of Health Istanbul Training and Research Hospital...

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Autores principales: Osman Yokus, Habip Gedik
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Lenguaje:EN
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2016
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Acceso en línea:https://doaj.org/article/051c9c89e68941038ca47f088b593537
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spelling oai:doaj.org-article:051c9c89e68941038ca47f088b5935372021-12-02T16:24:58ZEtiological causes of pancytopenia: A report of 137 cases2231-07702249-446410.4103/2231-0770.191447https://doaj.org/article/051c9c89e68941038ca47f088b5935372016-10-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.191447https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Objective: The aim of this study is to evaluate the etiological causes of pancytopenia in patients who were admitted to the hematology ward due to pancytopenia. Materials and Methods: All patients who were admitted to the hematology ward of Ministry of Health Istanbul Training and Research Hospital due to pancytopenia between 2013 and 2015 were retrospectively evaluated regarding etiological causes. Results: A total of 137 patients was evaluated. The etiological causes of pancytopenia were recorded as Vitamin B12 deficiency (n: 24; 17%), chronic liver disease (n: 21; 15%), malignancy (n: 19; 13%), myelodysplastic syndrome (n: 18; 13%), aplastic anemia (n: 11; 8%), rheumatic diseases (n: 7; 5%), and endocrine causes (n: 3; 2%). Conclusion: The etiological causes of pancytopenia vary depends on patients′ age, gender, country, and other conditions. Vitamin B12 deficiency is the most common treatable cause of pancytopenia. Most of the etiological causes could be diagnosed with laboratory analysis and radiological imagings, without the need of a bone marrow examination.Osman YokusHabip GedikThieme Medical and Scientific Publishers Pvt. Ltd.articlechronic liver diseasemyelodysplastic syndromepancytopeniavitamin b12 deficiencyMedicineRENAvicenna Journal of Medicine, Vol 06, Iss 04, Pp 109-112 (2016)
institution DOAJ
collection DOAJ
language EN
topic chronic liver disease
myelodysplastic syndrome
pancytopenia
vitamin b12 deficiency
Medicine
R
spellingShingle chronic liver disease
myelodysplastic syndrome
pancytopenia
vitamin b12 deficiency
Medicine
R
Osman Yokus
Habip Gedik
Etiological causes of pancytopenia: A report of 137 cases
description Objective: The aim of this study is to evaluate the etiological causes of pancytopenia in patients who were admitted to the hematology ward due to pancytopenia. Materials and Methods: All patients who were admitted to the hematology ward of Ministry of Health Istanbul Training and Research Hospital due to pancytopenia between 2013 and 2015 were retrospectively evaluated regarding etiological causes. Results: A total of 137 patients was evaluated. The etiological causes of pancytopenia were recorded as Vitamin B12 deficiency (n: 24; 17%), chronic liver disease (n: 21; 15%), malignancy (n: 19; 13%), myelodysplastic syndrome (n: 18; 13%), aplastic anemia (n: 11; 8%), rheumatic diseases (n: 7; 5%), and endocrine causes (n: 3; 2%). Conclusion: The etiological causes of pancytopenia vary depends on patients′ age, gender, country, and other conditions. Vitamin B12 deficiency is the most common treatable cause of pancytopenia. Most of the etiological causes could be diagnosed with laboratory analysis and radiological imagings, without the need of a bone marrow examination.
format article
author Osman Yokus
Habip Gedik
author_facet Osman Yokus
Habip Gedik
author_sort Osman Yokus
title Etiological causes of pancytopenia: A report of 137 cases
title_short Etiological causes of pancytopenia: A report of 137 cases
title_full Etiological causes of pancytopenia: A report of 137 cases
title_fullStr Etiological causes of pancytopenia: A report of 137 cases
title_full_unstemmed Etiological causes of pancytopenia: A report of 137 cases
title_sort etiological causes of pancytopenia: a report of 137 cases
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate 2016
url https://doaj.org/article/051c9c89e68941038ca47f088b593537
work_keys_str_mv AT osmanyokus etiologicalcausesofpancytopeniaareportof137cases
AT habipgedik etiologicalcausesofpancytopeniaareportof137cases
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