Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction

How nuclear architecture overall affects the replication-timing programme is not yet clear. Here the authors reveal RIF1’s dual role as a chromatin-interaction scaffold and regulator of replication timing that allows the coordination of these two aspects of nuclear function.

Guardado en:

Detalles Bibliográficos
Autores principales:	Stefano Gnan, Ilya M. Flyamer, Kyle N. Klein, Eleonora Castelli, Alexander Rapp, Andreas Maiser, Naiming Chen, Patrick Weber, Elin Enervald, M. Cristina Cardoso, Wendy A. Bickmore, David M. Gilbert, Sara C. B. Buonomo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/051ec9ea54774968bffcfc289db433ad
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:051ec9ea54774968bffcfc289db433ad
record_format	dspace
spelling	oai:doaj.org-article:051ec9ea54774968bffcfc289db433ad2021-12-02T15:45:13ZNuclear organisation and replication timing are coupled through RIF1–PP1 interaction10.1038/s41467-021-22899-22041-1723https://doaj.org/article/051ec9ea54774968bffcfc289db433ad2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22899-2https://doaj.org/toc/2041-1723How nuclear architecture overall affects the replication-timing programme is not yet clear. Here the authors reveal RIF1’s dual role as a chromatin-interaction scaffold and regulator of replication timing that allows the coordination of these two aspects of nuclear function.Stefano GnanIlya M. FlyamerKyle N. KleinEleonora CastelliAlexander RappAndreas MaiserNaiming ChenPatrick WeberElin EnervaldM. Cristina CardosoWendy A. BickmoreDavid M. GilbertSara C. B. BuonomoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stefano Gnan Ilya M. Flyamer Kyle N. Klein Eleonora Castelli Alexander Rapp Andreas Maiser Naiming Chen Patrick Weber Elin Enervald M. Cristina Cardoso Wendy A. Bickmore David M. Gilbert Sara C. B. Buonomo Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction
description	How nuclear architecture overall affects the replication-timing programme is not yet clear. Here the authors reveal RIF1’s dual role as a chromatin-interaction scaffold and regulator of replication timing that allows the coordination of these two aspects of nuclear function.
format	article
author	Stefano Gnan Ilya M. Flyamer Kyle N. Klein Eleonora Castelli Alexander Rapp Andreas Maiser Naiming Chen Patrick Weber Elin Enervald M. Cristina Cardoso Wendy A. Bickmore David M. Gilbert Sara C. B. Buonomo
author_facet	Stefano Gnan Ilya M. Flyamer Kyle N. Klein Eleonora Castelli Alexander Rapp Andreas Maiser Naiming Chen Patrick Weber Elin Enervald M. Cristina Cardoso Wendy A. Bickmore David M. Gilbert Sara C. B. Buonomo
author_sort	Stefano Gnan
title	Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction
title_short	Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction
title_full	Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction
title_fullStr	Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction
title_full_unstemmed	Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction
title_sort	nuclear organisation and replication timing are coupled through rif1–pp1 interaction
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/051ec9ea54774968bffcfc289db433ad
work_keys_str_mv	AT stefanognan nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT ilyamflyamer nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT kylenklein nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT eleonoracastelli nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT alexanderrapp nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT andreasmaiser nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT naimingchen nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT patrickweber nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT elinenervald nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT mcristinacardoso nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT wendyabickmore nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT davidmgilbert nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction AT saracbbuonomo nuclearorganisationandreplicationtimingarecoupledthroughrif1pp1interaction
_version_	1718385731385163776

Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction

Ejemplares similares