Protein kinase C θ regulates the phenotype of murine CD4+ Th17 cells.

Protein kinase C θ regulates the phenotype of murine CD4+ Th17 cells.

Protein kinase C θ (PKCθ) is involved in signaling downstream of the T cell antigen receptor (TCR) and is important for shaping effector T cell functions and inflammatory disease development. Acquisition of Th1-like effector features by Th17 cells has been linked to increased pathogenic potential. H...

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Autores principales: Katarzyna Wachowicz, Natascha Hermann-Kleiter, Marlies Meisel, Kerstin Siegmund, Nikolaus Thuille, Gottfried Baier
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/0527c39ada1f4a6cb2f597609a992302
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