Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds

Fast metabolisms tend to shorten lifespans by increasing oxidative damage. This study identifies a gene mutation that keeps a key antioxidant response active, possibly allowing Neoaves bird species to avoid the tradeoff between rapid metabolism and longevity that challenges most mammals, including h...

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Autores principales:	Gianni M. Castiglione, Zhenhua Xu, Lingli Zhou, Elia J. Duh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/052bff029c4a47f4a9278f810bbc446b
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spelling	oai:doaj.org-article:052bff029c4a47f4a9278f810bbc446b2021-12-02T16:51:25ZAdaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds10.1038/s41467-020-16129-42041-1723https://doaj.org/article/052bff029c4a47f4a9278f810bbc446b2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16129-4https://doaj.org/toc/2041-1723Fast metabolisms tend to shorten lifespans by increasing oxidative damage. This study identifies a gene mutation that keeps a key antioxidant response active, possibly allowing Neoaves bird species to avoid the tradeoff between rapid metabolism and longevity that challenges most mammals, including humans.Gianni M. CastiglioneZhenhua XuLingli ZhouElia J. DuhNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gianni M. Castiglione Zhenhua Xu Lingli Zhou Elia J. Duh Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds
description	Fast metabolisms tend to shorten lifespans by increasing oxidative damage. This study identifies a gene mutation that keeps a key antioxidant response active, possibly allowing Neoaves bird species to avoid the tradeoff between rapid metabolism and longevity that challenges most mammals, including humans.
format	article
author	Gianni M. Castiglione Zhenhua Xu Lingli Zhou Elia J. Duh
author_facet	Gianni M. Castiglione Zhenhua Xu Lingli Zhou Elia J. Duh
author_sort	Gianni M. Castiglione
title	Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds
title_short	Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds
title_full	Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds
title_fullStr	Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds
title_full_unstemmed	Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds
title_sort	adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/052bff029c4a47f4a9278f810bbc446b
work_keys_str_mv	AT giannimcastiglione adaptationofthemasterantioxidantresponseconnectsmetabolismlifespanandfeatherdevelopmentpathwaysinbirds AT zhenhuaxu adaptationofthemasterantioxidantresponseconnectsmetabolismlifespanandfeatherdevelopmentpathwaysinbirds AT linglizhou adaptationofthemasterantioxidantresponseconnectsmetabolismlifespanandfeatherdevelopmentpathwaysinbirds AT eliajduh adaptationofthemasterantioxidantresponseconnectsmetabolismlifespanandfeatherdevelopmentpathwaysinbirds
_version_	1718382958742601728

Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds

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