Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan

Age at voice-breaking is used to determine puberty timing in men, recall of which is considered less accurate than age at first menarche in women. Here, the authors perform multi-trait GWAS for male puberty timing by including both age at voice breaking and age of first facial hair for improved phen...

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Autores principales: Ben Hollis, Felix R. Day, Alexander S. Busch, Deborah J. Thompson, Ana Luiza G. Soares, Paul R. H. J. Timmers, Alex Kwong, Doug F. Easton, Peter K. Joshi, Nicholas J. Timpson, The PRACTICAL Consortium, 23andMe Research Team, Ken K. Ong, John R. B. Perry
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/052dee7053834455beecef916b0d9d00
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spelling oai:doaj.org-article:052dee7053834455beecef916b0d9d002021-12-02T17:33:12ZGenomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan10.1038/s41467-020-14451-52041-1723https://doaj.org/article/052dee7053834455beecef916b0d9d002020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14451-5https://doaj.org/toc/2041-1723Age at voice-breaking is used to determine puberty timing in men, recall of which is considered less accurate than age at first menarche in women. Here, the authors perform multi-trait GWAS for male puberty timing by including both age at voice breaking and age of first facial hair for improved phenotype definition and power.Ben HollisFelix R. DayAlexander S. BuschDeborah J. ThompsonAna Luiza G. SoaresPaul R. H. J. TimmersAlex KwongDoug F. EastonPeter K. JoshiNicholas J. TimpsonThe PRACTICAL Consortium23andMe Research TeamKen K. OngJohn R. B. PerryNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ben Hollis
Felix R. Day
Alexander S. Busch
Deborah J. Thompson
Ana Luiza G. Soares
Paul R. H. J. Timmers
Alex Kwong
Doug F. Easton
Peter K. Joshi
Nicholas J. Timpson
The PRACTICAL Consortium
23andMe Research Team
Ken K. Ong
John R. B. Perry
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan
description Age at voice-breaking is used to determine puberty timing in men, recall of which is considered less accurate than age at first menarche in women. Here, the authors perform multi-trait GWAS for male puberty timing by including both age at voice breaking and age of first facial hair for improved phenotype definition and power.
format article
author Ben Hollis
Felix R. Day
Alexander S. Busch
Deborah J. Thompson
Ana Luiza G. Soares
Paul R. H. J. Timmers
Alex Kwong
Doug F. Easton
Peter K. Joshi
Nicholas J. Timpson
The PRACTICAL Consortium
23andMe Research Team
Ken K. Ong
John R. B. Perry
author_facet Ben Hollis
Felix R. Day
Alexander S. Busch
Deborah J. Thompson
Ana Luiza G. Soares
Paul R. H. J. Timmers
Alex Kwong
Doug F. Easton
Peter K. Joshi
Nicholas J. Timpson
The PRACTICAL Consortium
23andMe Research Team
Ken K. Ong
John R. B. Perry
author_sort Ben Hollis
title Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan
title_short Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan
title_full Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan
title_fullStr Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan
title_full_unstemmed Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan
title_sort genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/052dee7053834455beecef916b0d9d00
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