Ambient oxygen promotes tumorigenesis.

Oxygen serves as an essential factor for oxidative stress, and it has been shown to be a mutagen in bacteria. While it is well established that ambient oxygen can also cause genomic instability in cultured mammalian cells, its effect on de novo tumorigenesis at the organismal level is unclear. Herei...

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Autores principales: Ho Joong Sung, Wenzhe Ma, Matthew F Starost, Cory U Lago, Philip K Lim, Michael N Sack, Ju-Gyeong Kang, Ping-yuan Wang, Paul M Hwang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/053088453a644174baa3e73f90b6fae0
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