Human Cytomegalovirus (HCMV) Glycoprotein gB Promotes Virus Entry In <italic toggle="yes">Trans</italic> Acting as the Viral Fusion Protein Rather than as a Receptor-Binding Protein

Human Cytomegalovirus (HCMV) Glycoprotein gB Promotes Virus Entry In <italic toggle="yes">Trans</italic> Acting as the Viral Fusion Protein Rather than as a Receptor-Binding Protein

ABSTRACT Human cytomegalovirus (HCMV) glycoproteins gB and gH/gL are both necessary and sufficient for cell-cell fusion. However, it is not clear what roles these glycoproteins play in virus entry, whether acting directly in membrane fusion or in binding receptors. With other herpesviruses, it appea...

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Autores principales: Paul T. Wille, Todd W. Wisner, Brent Ryckman, David C. Johnson
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2013
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/0531c9c615b847cda9893946045f0291
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