NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization

NEK7 is a kinase known for its role in mitotic spindle assembly, driving centrosome separation in prophase through regulation of the kinesin Eg5. Here, the authors show that NEK7 and Eg5 also control dendrite morphogenesis in postmitotic neurons.

Guardado en:

Detalles Bibliográficos
Autores principales:	Francisco Freixo, Paula Martinez Delgado, Yasmina Manso, Carlos Sánchez-Huertas, Cristina Lacasa, Eduardo Soriano, Joan Roig, Jens Lüders
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/053282e29ed4414bbaf05118740ff4ed
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:053282e29ed4414bbaf05118740ff4ed
record_format	dspace
spelling	oai:doaj.org-article:053282e29ed4414bbaf05118740ff4ed2021-12-02T15:34:49ZNEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization10.1038/s41467-018-04706-72041-1723https://doaj.org/article/053282e29ed4414bbaf05118740ff4ed2018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04706-7https://doaj.org/toc/2041-1723NEK7 is a kinase known for its role in mitotic spindle assembly, driving centrosome separation in prophase through regulation of the kinesin Eg5. Here, the authors show that NEK7 and Eg5 also control dendrite morphogenesis in postmitotic neurons.Francisco FreixoPaula Martinez DelgadoYasmina MansoCarlos Sánchez-HuertasCristina LacasaEduardo SorianoJoan RoigJens LüdersNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Francisco Freixo Paula Martinez Delgado Yasmina Manso Carlos Sánchez-Huertas Cristina Lacasa Eduardo Soriano Joan Roig Jens Lüders NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization
description	NEK7 is a kinase known for its role in mitotic spindle assembly, driving centrosome separation in prophase through regulation of the kinesin Eg5. Here, the authors show that NEK7 and Eg5 also control dendrite morphogenesis in postmitotic neurons.
format	article
author	Francisco Freixo Paula Martinez Delgado Yasmina Manso Carlos Sánchez-Huertas Cristina Lacasa Eduardo Soriano Joan Roig Jens Lüders
author_facet	Francisco Freixo Paula Martinez Delgado Yasmina Manso Carlos Sánchez-Huertas Cristina Lacasa Eduardo Soriano Joan Roig Jens Lüders
author_sort	Francisco Freixo
title	NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization
title_short	NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization
title_full	NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization
title_fullStr	NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization
title_full_unstemmed	NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization
title_sort	nek7 regulates dendrite morphogenesis in neurons via eg5-dependent microtubule stabilization
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/053282e29ed4414bbaf05118740ff4ed
work_keys_str_mv	AT franciscofreixo nek7regulatesdendritemorphogenesisinneuronsviaeg5dependentmicrotubulestabilization AT paulamartinezdelgado nek7regulatesdendritemorphogenesisinneuronsviaeg5dependentmicrotubulestabilization AT yasminamanso nek7regulatesdendritemorphogenesisinneuronsviaeg5dependentmicrotubulestabilization AT carlossanchezhuertas nek7regulatesdendritemorphogenesisinneuronsviaeg5dependentmicrotubulestabilization AT cristinalacasa nek7regulatesdendritemorphogenesisinneuronsviaeg5dependentmicrotubulestabilization AT eduardosoriano nek7regulatesdendritemorphogenesisinneuronsviaeg5dependentmicrotubulestabilization AT joanroig nek7regulatesdendritemorphogenesisinneuronsviaeg5dependentmicrotubulestabilization AT jensluders nek7regulatesdendritemorphogenesisinneuronsviaeg5dependentmicrotubulestabilization
_version_	1718386698855907328

NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization

Ejemplares similares