NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization

NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization

NEK7 is a kinase known for its role in mitotic spindle assembly, driving centrosome separation in prophase through regulation of the kinesin Eg5. Here, the authors show that NEK7 and Eg5 also control dendrite morphogenesis in postmitotic neurons.

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Autores principales: Francisco Freixo, Paula Martinez Delgado, Yasmina Manso, Carlos Sánchez-Huertas, Cristina Lacasa, Eduardo Soriano, Joan Roig, Jens Lüders
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
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Acceso en línea:https://doaj.org/article/053282e29ed4414bbaf05118740ff4ed
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