Time to Antiretroviral Therapy Initiation and Its Predictors Among Newly Diagnosed HIV-Positive People in Nekemte Town, Western Ethiopia: Claim of Universal Test and Treat

Lami Bayisa,1 Tesfaye Abera,1 Diriba Mulisa,1 Getu Mosisa,1 Alemnesh Mosisa,1 Tadesse Tolosa,2 Ebisa Turi,2 Bizuneh Wakuma,3 Eba Abdisa,1 Diriba Bayisa4 1Department of Nursing, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia; 2Department of Public Health, Institutes of Health Sci...

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Autores principales:	Bayisa L, Abera T, Mulisa D, Mosisa G, Mosisa A, Tolosa T, Turi E, Wakuma B, Abdisa E, Bayisa D
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	art initiation time to art initiation newly diagnosed hiv positive ethiopia Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/05339350526246d49d65c45c99c51e5a
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spelling	oai:doaj.org-article:05339350526246d49d65c45c99c51e5a2021-12-02T19:16:30ZTime to Antiretroviral Therapy Initiation and Its Predictors Among Newly Diagnosed HIV-Positive People in Nekemte Town, Western Ethiopia: Claim of Universal Test and Treat1179-1373https://doaj.org/article/05339350526246d49d65c45c99c51e5a2021-10-01T00:00:00Zhttps://www.dovepress.com/time-to-antiretroviral-therapy-initiation-and-its-predictors-among-new-peer-reviewed-fulltext-article-HIVhttps://doaj.org/toc/1179-1373Lami Bayisa,1 Tesfaye Abera,1 Diriba Mulisa,1 Getu Mosisa,1 Alemnesh Mosisa,1 Tadesse Tolosa,2 Ebisa Turi,2 Bizuneh Wakuma,3 Eba Abdisa,1 Diriba Bayisa4 1Department of Nursing, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia; 2Department of Public Health, Institutes of Health Sciences, Wollega University, Nekemte, Ethiopia; 3Department of Pediatric Nursing, Institutes of Health Sciences, Wollega University, Nekemte, Ethiopia; 4Department of Midwifery, Institutes of Health Sciences, Wollega University, Nekemte, EthiopiaCorrespondence: Lami BayisaDepartment of Nursing, Institutes of Health Sciences, Wollega University, P.O. Box: 395, Nekemte, EthiopiaTel +251 924318135Email lamisabayisa@gmail.comBackground: HIV continuum of care demands early ART initiation for all HIV-infected individuals. Early ART initiation reduces onward HIV transmission facilitating rapid viral suppression. Despite this, delayed ART use is a challenge among newly diagnosed HIV-positive individuals, and there is limited evidence on time to ART initiation among this group in Ethiopia. Thus, this study aimed to assess time to ART initiation and its predictors among newly diagnosed HIV-positive individuals in Nekemte town, Western Ethiopia.Methods: An institution-based retrospective follow-up study was conducted on 518 newly diagnosed HIV-positive people from September 5, 2016 to December 20, 2020 at Nekemte town, Western Ethiopia. Data were collected from ART intake forms, registration log books and patient charts. The collected data were entered into Epi Data version 3.1 and STATA version 14.0 was used for analysis. Survival probability was checked graphically by Kaplan–Meier curve and statistically by Log rank test. Both bivariable and multivariable Cox Proportional hazards regression models were conducted to identify the predictors of ART initiation. Hazard ratio with 95% CI and p-value of < 0.05 was used to declare a statistical significance.Results: By the end of the follow-up, 371 (71.6%) individuals had initiated ART with an overall incidence rate of 51.9 per 1000 [95% CI: 54.07– 66.32] person days; median time to ART initiation was 4 [IQR: 1– 9] days. Being female (AHR = 1.33, 95% CI: 1.06– 1.67), urban dwellers (AHR = 2.02, 95% CI: 1.37– 2.97), having baseline OIs (AHR = 1.62, 95% CI: 1.60– 4.30); being tested via VCT (AHR = 1.33, 95% CI: 1.02– 1.74); linked from OPD (AHR = 0.64, 95% CI: 0.47– 0.85); disclosing HIV sero-status (AHR = 2.07, 95% CI: 1.17– 3.68); and college and above education level (AHR = 1.43, 95% CI: 1.00– 2.0) were identified as significant predictors of early initiation of ART.Conclusion: The proportion and incidence of ART initiation was high; a short median time to ART initiation was revealed in this study. Strictly screening OIs, encouraging HIV sero-status disclosure and voluntary HIV testing are recommended to increase early ART initiation.Keywords: ART initiation, time to ART initiation, newly diagnosed HIV positive, EthiopiaBayisa LAbera TMulisa DMosisa GMosisa ATolosa TTuri EWakuma BAbdisa EBayisa DDove Medical Pressarticleart initiationtime to art initiationnewly diagnosed hiv positiveethiopiaImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol Volume 13, Pp 959-972 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	art initiation time to art initiation newly diagnosed hiv positive ethiopia Immunologic diseases. Allergy RC581-607
spellingShingle	art initiation time to art initiation newly diagnosed hiv positive ethiopia Immunologic diseases. Allergy RC581-607 Bayisa L Abera T Mulisa D Mosisa G Mosisa A Tolosa T Turi E Wakuma B Abdisa E Bayisa D Time to Antiretroviral Therapy Initiation and Its Predictors Among Newly Diagnosed HIV-Positive People in Nekemte Town, Western Ethiopia: Claim of Universal Test and Treat
description	Lami Bayisa,1 Tesfaye Abera,1 Diriba Mulisa,1 Getu Mosisa,1 Alemnesh Mosisa,1 Tadesse Tolosa,2 Ebisa Turi,2 Bizuneh Wakuma,3 Eba Abdisa,1 Diriba Bayisa4 1Department of Nursing, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia; 2Department of Public Health, Institutes of Health Sciences, Wollega University, Nekemte, Ethiopia; 3Department of Pediatric Nursing, Institutes of Health Sciences, Wollega University, Nekemte, Ethiopia; 4Department of Midwifery, Institutes of Health Sciences, Wollega University, Nekemte, EthiopiaCorrespondence: Lami BayisaDepartment of Nursing, Institutes of Health Sciences, Wollega University, P.O. Box: 395, Nekemte, EthiopiaTel +251 924318135Email lamisabayisa@gmail.comBackground: HIV continuum of care demands early ART initiation for all HIV-infected individuals. Early ART initiation reduces onward HIV transmission facilitating rapid viral suppression. Despite this, delayed ART use is a challenge among newly diagnosed HIV-positive individuals, and there is limited evidence on time to ART initiation among this group in Ethiopia. Thus, this study aimed to assess time to ART initiation and its predictors among newly diagnosed HIV-positive individuals in Nekemte town, Western Ethiopia.Methods: An institution-based retrospective follow-up study was conducted on 518 newly diagnosed HIV-positive people from September 5, 2016 to December 20, 2020 at Nekemte town, Western Ethiopia. Data were collected from ART intake forms, registration log books and patient charts. The collected data were entered into Epi Data version 3.1 and STATA version 14.0 was used for analysis. Survival probability was checked graphically by Kaplan–Meier curve and statistically by Log rank test. Both bivariable and multivariable Cox Proportional hazards regression models were conducted to identify the predictors of ART initiation. Hazard ratio with 95% CI and p-value of < 0.05 was used to declare a statistical significance.Results: By the end of the follow-up, 371 (71.6%) individuals had initiated ART with an overall incidence rate of 51.9 per 1000 [95% CI: 54.07– 66.32] person days; median time to ART initiation was 4 [IQR: 1– 9] days. Being female (AHR = 1.33, 95% CI: 1.06– 1.67), urban dwellers (AHR = 2.02, 95% CI: 1.37– 2.97), having baseline OIs (AHR = 1.62, 95% CI: 1.60– 4.30); being tested via VCT (AHR = 1.33, 95% CI: 1.02– 1.74); linked from OPD (AHR = 0.64, 95% CI: 0.47– 0.85); disclosing HIV sero-status (AHR = 2.07, 95% CI: 1.17– 3.68); and college and above education level (AHR = 1.43, 95% CI: 1.00– 2.0) were identified as significant predictors of early initiation of ART.Conclusion: The proportion and incidence of ART initiation was high; a short median time to ART initiation was revealed in this study. Strictly screening OIs, encouraging HIV sero-status disclosure and voluntary HIV testing are recommended to increase early ART initiation.Keywords: ART initiation, time to ART initiation, newly diagnosed HIV positive, Ethiopia
format	article
author	Bayisa L Abera T Mulisa D Mosisa G Mosisa A Tolosa T Turi E Wakuma B Abdisa E Bayisa D
author_facet	Bayisa L Abera T Mulisa D Mosisa G Mosisa A Tolosa T Turi E Wakuma B Abdisa E Bayisa D
author_sort	Bayisa L
title	Time to Antiretroviral Therapy Initiation and Its Predictors Among Newly Diagnosed HIV-Positive People in Nekemte Town, Western Ethiopia: Claim of Universal Test and Treat
title_short	Time to Antiretroviral Therapy Initiation and Its Predictors Among Newly Diagnosed HIV-Positive People in Nekemte Town, Western Ethiopia: Claim of Universal Test and Treat
title_full	Time to Antiretroviral Therapy Initiation and Its Predictors Among Newly Diagnosed HIV-Positive People in Nekemte Town, Western Ethiopia: Claim of Universal Test and Treat
title_fullStr	Time to Antiretroviral Therapy Initiation and Its Predictors Among Newly Diagnosed HIV-Positive People in Nekemte Town, Western Ethiopia: Claim of Universal Test and Treat
title_full_unstemmed	Time to Antiretroviral Therapy Initiation and Its Predictors Among Newly Diagnosed HIV-Positive People in Nekemte Town, Western Ethiopia: Claim of Universal Test and Treat
title_sort	time to antiretroviral therapy initiation and its predictors among newly diagnosed hiv-positive people in nekemte town, western ethiopia: claim of universal test and treat
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/05339350526246d49d65c45c99c51e5a
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Time to Antiretroviral Therapy Initiation and Its Predictors Among Newly Diagnosed HIV-Positive People in Nekemte Town, Western Ethiopia: Claim of Universal Test and Treat

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