A molecular epidemiology survey of respiratory adenoviruses circulating in children residing in Southern Palestine.

A molecular epidemiology survey was performed in order to establish and document the respiratory adenovirus pathogen profiles among children in Southern Palestine. Three hundred and thirty-eight hospitalized pediatric cases with adenovirus-associated respiratory tract infections were analyzed. Forty...

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Autores principales: Lina Qurei, Donald Seto, Zaidoun Salah, Maysa Azzeh
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Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/05368e863b34483ca99a34eb15762e18
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spelling oai:doaj.org-article:05368e863b34483ca99a34eb15762e182021-11-18T07:09:39ZA molecular epidemiology survey of respiratory adenoviruses circulating in children residing in Southern Palestine.1932-620310.1371/journal.pone.0042732https://doaj.org/article/05368e863b34483ca99a34eb15762e182012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22880092/?tool=EBIhttps://doaj.org/toc/1932-6203A molecular epidemiology survey was performed in order to establish and document the respiratory adenovirus pathogen profiles among children in Southern Palestine. Three hundred and thirty-eight hospitalized pediatric cases with adenovirus-associated respiratory tract infections were analyzed. Forty four cases out of the 338 were evaluated in more detail for the adenoviruses types present. All of the children resided in Southern Palestine, that is, in city, village and refugee camp environments within the districts of Hebron and Bethlehem. Human adenoviruses circulated throughout 2005-2010, with major outbreaks occurring in the spring months. A larger percent of the children diagnosed with adenoviral infections were male infants. DNA sequence analysis of the hexon genes from 44 samples revealed that several distinct adenovirus types circulated in the region; these were HAdV-C1, HAdV-C2, HAdV-B3 and HAdV-C5. However, not all of these types were detected within each year. This is the first study ever conducted in Palestine of the genetic epidemiology of respiratory adenovirus infections.Lina QureiDonald SetoZaidoun SalahMaysa AzzehPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 8, p e42732 (2012)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Lina Qurei
Donald Seto
Zaidoun Salah
Maysa Azzeh
A molecular epidemiology survey of respiratory adenoviruses circulating in children residing in Southern Palestine.
description A molecular epidemiology survey was performed in order to establish and document the respiratory adenovirus pathogen profiles among children in Southern Palestine. Three hundred and thirty-eight hospitalized pediatric cases with adenovirus-associated respiratory tract infections were analyzed. Forty four cases out of the 338 were evaluated in more detail for the adenoviruses types present. All of the children resided in Southern Palestine, that is, in city, village and refugee camp environments within the districts of Hebron and Bethlehem. Human adenoviruses circulated throughout 2005-2010, with major outbreaks occurring in the spring months. A larger percent of the children diagnosed with adenoviral infections were male infants. DNA sequence analysis of the hexon genes from 44 samples revealed that several distinct adenovirus types circulated in the region; these were HAdV-C1, HAdV-C2, HAdV-B3 and HAdV-C5. However, not all of these types were detected within each year. This is the first study ever conducted in Palestine of the genetic epidemiology of respiratory adenovirus infections.
format article
author Lina Qurei
Donald Seto
Zaidoun Salah
Maysa Azzeh
author_facet Lina Qurei
Donald Seto
Zaidoun Salah
Maysa Azzeh
author_sort Lina Qurei
title A molecular epidemiology survey of respiratory adenoviruses circulating in children residing in Southern Palestine.
title_short A molecular epidemiology survey of respiratory adenoviruses circulating in children residing in Southern Palestine.
title_full A molecular epidemiology survey of respiratory adenoviruses circulating in children residing in Southern Palestine.
title_fullStr A molecular epidemiology survey of respiratory adenoviruses circulating in children residing in Southern Palestine.
title_full_unstemmed A molecular epidemiology survey of respiratory adenoviruses circulating in children residing in Southern Palestine.
title_sort molecular epidemiology survey of respiratory adenoviruses circulating in children residing in southern palestine.
publisher Public Library of Science (PLoS)
publishDate 2012
url https://doaj.org/article/05368e863b34483ca99a34eb15762e18
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AT zaidounsalah amolecularepidemiologysurveyofrespiratoryadenovirusescirculatinginchildrenresidinginsouthernpalestine
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