Gut Microbiota and Their Derived Metabolites, a Search for Potential Targets to Limit Accumulation of Protein-Bound Uremic Toxins in Chronic Kidney Disease

Gut Microbiota and Their Derived Metabolites, a Search for Potential Targets to Limit Accumulation of Protein-Bound Uremic Toxins in Chronic Kidney Disease

Chronic kidney disease (CKD) is characterized by gut dysbiosis with a decrease in short-chain fatty acid (SCFA)-producing bacteria. Levels of protein-bound uremic toxins (PBUTs) and post-translational modifications (PTMs) of albumin increase with CKD, both risk factors for cardiovascular morbidity a...

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Bibliographic Details
Main Authors: Mieke Steenbeke, Sophie Valkenburg, Tessa Gryp, Wim Van Biesen, Joris R. Delanghe, Marijn M. Speeckaert, Griet Glorieux
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
chronic kidney disease
uremic toxins
short-chain fatty acids (SCFAs)
albumin symmetry factor
fecal samples
Medicine
R
Online Access:https://doaj.org/article/0537b022e8b3467bbb75822ecd4032c8
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https://doaj.org/article/0537b022e8b3467bbb75822ecd4032c8

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