An Overview of Selected Rare B-Cell Lymphoproliferative Disorders: Imaging, Histopathologic, and Clinical Features
Lymphoproliferative disorders (LPD) are conditions characterized by the uncontrolled proliferation of B or T-cell lines. They encompass a wide spectrum of abnormalities, which may be broadly classified as reactive processes or malignant diseases, such as lymphoma, based on their cellular clonality a...
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oai:doaj.org-article:053d973fce5b4c499accbea9950333f02021-11-25T17:04:45ZAn Overview of Selected Rare B-Cell Lymphoproliferative Disorders: Imaging, Histopathologic, and Clinical Features10.3390/cancers132258532072-6694https://doaj.org/article/053d973fce5b4c499accbea9950333f02021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/22/5853https://doaj.org/toc/2072-6694Lymphoproliferative disorders (LPD) are conditions characterized by the uncontrolled proliferation of B or T-cell lines. They encompass a wide spectrum of abnormalities, which may be broadly classified as reactive processes or malignant diseases, such as lymphoma, based on their cellular clonality and clinical behavior. While some of these disorders are rare, they may be encountered sporadically in clinical practice, causing diagnostic dilemmas owing to overlap in their clinical and imaging features with more common disorders. The updated 4th edition WHO classification of lymphoid neoplasms was released in 2016 to incorporate the rapid clinical, pathological, molecular biology and cytogenetic advances of some of these disorders. Despite these updates, very little information is presented in the literature from the radiology perspective. The aim of this article is to familiarize radiologists and other physicians with certain rare variants of B-cell lymphoproliferative disorders with a focus on imaging features of these disorders, as well as to provide an overview of some important updates contained within the new WHO classification of lymphoid neoplasms.Ahmed Ebada SalemYehia H. ZakiGamal El-HussienyKhaled I. ElNoueamAkram M. ShaabanBhasker Rao KoppulaMark BustorosMohamed SalamaKhaled M. ElsayesKathryn MortonMatthew F. CovingtonMDPI AGarticleupdatesWHO classification of hematologic malignancieslymphoproliferative disordersrare B-cell lymphomas18F-FDG PET/CTNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5853, p 5853 (2021) |
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updates WHO classification of hematologic malignancies lymphoproliferative disorders rare B-cell lymphomas 18F-FDG PET/CT Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
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updates WHO classification of hematologic malignancies lymphoproliferative disorders rare B-cell lymphomas 18F-FDG PET/CT Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Ahmed Ebada Salem Yehia H. Zaki Gamal El-Hussieny Khaled I. ElNoueam Akram M. Shaaban Bhasker Rao Koppula Mark Bustoros Mohamed Salama Khaled M. Elsayes Kathryn Morton Matthew F. Covington An Overview of Selected Rare B-Cell Lymphoproliferative Disorders: Imaging, Histopathologic, and Clinical Features |
description |
Lymphoproliferative disorders (LPD) are conditions characterized by the uncontrolled proliferation of B or T-cell lines. They encompass a wide spectrum of abnormalities, which may be broadly classified as reactive processes or malignant diseases, such as lymphoma, based on their cellular clonality and clinical behavior. While some of these disorders are rare, they may be encountered sporadically in clinical practice, causing diagnostic dilemmas owing to overlap in their clinical and imaging features with more common disorders. The updated 4th edition WHO classification of lymphoid neoplasms was released in 2016 to incorporate the rapid clinical, pathological, molecular biology and cytogenetic advances of some of these disorders. Despite these updates, very little information is presented in the literature from the radiology perspective. The aim of this article is to familiarize radiologists and other physicians with certain rare variants of B-cell lymphoproliferative disorders with a focus on imaging features of these disorders, as well as to provide an overview of some important updates contained within the new WHO classification of lymphoid neoplasms. |
format |
article |
author |
Ahmed Ebada Salem Yehia H. Zaki Gamal El-Hussieny Khaled I. ElNoueam Akram M. Shaaban Bhasker Rao Koppula Mark Bustoros Mohamed Salama Khaled M. Elsayes Kathryn Morton Matthew F. Covington |
author_facet |
Ahmed Ebada Salem Yehia H. Zaki Gamal El-Hussieny Khaled I. ElNoueam Akram M. Shaaban Bhasker Rao Koppula Mark Bustoros Mohamed Salama Khaled M. Elsayes Kathryn Morton Matthew F. Covington |
author_sort |
Ahmed Ebada Salem |
title |
An Overview of Selected Rare B-Cell Lymphoproliferative Disorders: Imaging, Histopathologic, and Clinical Features |
title_short |
An Overview of Selected Rare B-Cell Lymphoproliferative Disorders: Imaging, Histopathologic, and Clinical Features |
title_full |
An Overview of Selected Rare B-Cell Lymphoproliferative Disorders: Imaging, Histopathologic, and Clinical Features |
title_fullStr |
An Overview of Selected Rare B-Cell Lymphoproliferative Disorders: Imaging, Histopathologic, and Clinical Features |
title_full_unstemmed |
An Overview of Selected Rare B-Cell Lymphoproliferative Disorders: Imaging, Histopathologic, and Clinical Features |
title_sort |
overview of selected rare b-cell lymphoproliferative disorders: imaging, histopathologic, and clinical features |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/053d973fce5b4c499accbea9950333f0 |
work_keys_str_mv |
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