Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute

Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute

Argonaute proteins are important in the silencing machinery with some regulatory RNAs. Here, the authors solve the structure of an argonaute protein in complex with both the guide RNA and target DNA and propose a mechanism for their recognition.

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Detalles Bibliográficos
Autores principales: Tomohiro Miyoshi, Kosuke Ito, Ryo Murakami, Toshio Uchiumi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/0546337e1548436bbd5fd7bc57a030cc
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