Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms

The mechanism underlying periodicity of Plasmodium’s intra-erythrocytic developmental cycle (IDC) is unclear. Here, Subudhi et al. show that serpentine receptor 10 (SR10) plays a role in regulating the schedule of the IDC in line with the timing of host daily rhythms.

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Autores principales: Amit K. Subudhi, Aidan J. O’Donnell, Abhinay Ramaprasad, Hussein M. Abkallo, Abhinav Kaushik, Hifzur R. Ansari, Alyaa M. Abdel-Haleem, Fathia Ben Rached, Osamu Kaneko, Richard Culleton, Sarah E. Reece, Arnab Pain
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/054dfacd7e3f4feb8fed1b8517913e0a
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spelling oai:doaj.org-article:054dfacd7e3f4feb8fed1b8517913e0a2021-12-02T15:02:55ZMalaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms10.1038/s41467-020-16593-y2041-1723https://doaj.org/article/054dfacd7e3f4feb8fed1b8517913e0a2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16593-yhttps://doaj.org/toc/2041-1723The mechanism underlying periodicity of Plasmodium’s intra-erythrocytic developmental cycle (IDC) is unclear. Here, Subudhi et al. show that serpentine receptor 10 (SR10) plays a role in regulating the schedule of the IDC in line with the timing of host daily rhythms.Amit K. SubudhiAidan J. O’DonnellAbhinay RamaprasadHussein M. AbkalloAbhinav KaushikHifzur R. AnsariAlyaa M. Abdel-HaleemFathia Ben RachedOsamu KanekoRichard CulletonSarah E. ReeceArnab PainNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Amit K. Subudhi
Aidan J. O’Donnell
Abhinay Ramaprasad
Hussein M. Abkallo
Abhinav Kaushik
Hifzur R. Ansari
Alyaa M. Abdel-Haleem
Fathia Ben Rached
Osamu Kaneko
Richard Culleton
Sarah E. Reece
Arnab Pain
Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms
description The mechanism underlying periodicity of Plasmodium’s intra-erythrocytic developmental cycle (IDC) is unclear. Here, Subudhi et al. show that serpentine receptor 10 (SR10) plays a role in regulating the schedule of the IDC in line with the timing of host daily rhythms.
format article
author Amit K. Subudhi
Aidan J. O’Donnell
Abhinay Ramaprasad
Hussein M. Abkallo
Abhinav Kaushik
Hifzur R. Ansari
Alyaa M. Abdel-Haleem
Fathia Ben Rached
Osamu Kaneko
Richard Culleton
Sarah E. Reece
Arnab Pain
author_facet Amit K. Subudhi
Aidan J. O’Donnell
Abhinay Ramaprasad
Hussein M. Abkallo
Abhinav Kaushik
Hifzur R. Ansari
Alyaa M. Abdel-Haleem
Fathia Ben Rached
Osamu Kaneko
Richard Culleton
Sarah E. Reece
Arnab Pain
author_sort Amit K. Subudhi
title Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms
title_short Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms
title_full Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms
title_fullStr Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms
title_full_unstemmed Malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms
title_sort malaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/054dfacd7e3f4feb8fed1b8517913e0a
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