A UGT1A1 variant is associated with serum total bilirubin levels, which are causal for hypertension in African-ancestry individuals

A UGT1A1 variant is associated with serum total bilirubin levels, which are causal for hypertension in African-ancestry individuals

Abstract Serum bilirubin is associated with several clinical outcomes, including hypertension, type 2 diabetes (T2D), and drug metabolism. Here, we describe findings from our genome-wide association studies (GWAS) of serum (TBIL) using a generalized linear mixed model in West Africans (n = 1127), wi...

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Autores principales: Guanjie Chen, Adebowale Adeyemo, Jie Zhou, Ayo P. Doumatey, Amy R. Bentley, Kenneth Ekoru, Daniel Shriner, Charles N. Rotimi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/054ecbf06a9d4a039ab5149e2fa661c4
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