Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells

Pluripotent stem cell colonies are encircled by large cornerstone focal adhesions (FAs). Here, using super-resolution imaging, the authors describe features in the nanoscale makeup of these stable FAs such as inverted vinculin, lateral talin segregation and distinct kank protein distributions.

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Autores principales: Aki Stubb, Camilo Guzmán, Elisa Närvä, Jesse Aaron, Teng-Leong Chew, Markku Saari, Mitro Miihkinen, Guillaume Jacquemet, Johanna Ivaska
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/054ff7d405564aaf959a9efd06915fc4
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spelling oai:doaj.org-article:054ff7d405564aaf959a9efd06915fc42021-12-02T17:01:28ZSuperresolution architecture of cornerstone focal adhesions in human pluripotent stem cells10.1038/s41467-019-12611-w2041-1723https://doaj.org/article/054ff7d405564aaf959a9efd06915fc42019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12611-whttps://doaj.org/toc/2041-1723Pluripotent stem cell colonies are encircled by large cornerstone focal adhesions (FAs). Here, using super-resolution imaging, the authors describe features in the nanoscale makeup of these stable FAs such as inverted vinculin, lateral talin segregation and distinct kank protein distributions.Aki StubbCamilo GuzmánElisa NärväJesse AaronTeng-Leong ChewMarkku SaariMitro MiihkinenGuillaume JacquemetJohanna IvaskaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aki Stubb
Camilo Guzmán
Elisa Närvä
Jesse Aaron
Teng-Leong Chew
Markku Saari
Mitro Miihkinen
Guillaume Jacquemet
Johanna Ivaska
Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
description Pluripotent stem cell colonies are encircled by large cornerstone focal adhesions (FAs). Here, using super-resolution imaging, the authors describe features in the nanoscale makeup of these stable FAs such as inverted vinculin, lateral talin segregation and distinct kank protein distributions.
format article
author Aki Stubb
Camilo Guzmán
Elisa Närvä
Jesse Aaron
Teng-Leong Chew
Markku Saari
Mitro Miihkinen
Guillaume Jacquemet
Johanna Ivaska
author_facet Aki Stubb
Camilo Guzmán
Elisa Närvä
Jesse Aaron
Teng-Leong Chew
Markku Saari
Mitro Miihkinen
Guillaume Jacquemet
Johanna Ivaska
author_sort Aki Stubb
title Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
title_short Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
title_full Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
title_fullStr Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
title_full_unstemmed Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
title_sort superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/054ff7d405564aaf959a9efd06915fc4
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