Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
Pluripotent stem cell colonies are encircled by large cornerstone focal adhesions (FAs). Here, using super-resolution imaging, the authors describe features in the nanoscale makeup of these stable FAs such as inverted vinculin, lateral talin segregation and distinct kank protein distributions.
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Nature Portfolio
2019
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oai:doaj.org-article:054ff7d405564aaf959a9efd06915fc42021-12-02T17:01:28ZSuperresolution architecture of cornerstone focal adhesions in human pluripotent stem cells10.1038/s41467-019-12611-w2041-1723https://doaj.org/article/054ff7d405564aaf959a9efd06915fc42019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12611-whttps://doaj.org/toc/2041-1723Pluripotent stem cell colonies are encircled by large cornerstone focal adhesions (FAs). Here, using super-resolution imaging, the authors describe features in the nanoscale makeup of these stable FAs such as inverted vinculin, lateral talin segregation and distinct kank protein distributions.Aki StubbCamilo GuzmánElisa NärväJesse AaronTeng-Leong ChewMarkku SaariMitro MiihkinenGuillaume JacquemetJohanna IvaskaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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Science Q Aki Stubb Camilo Guzmán Elisa Närvä Jesse Aaron Teng-Leong Chew Markku Saari Mitro Miihkinen Guillaume Jacquemet Johanna Ivaska Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells |
description |
Pluripotent stem cell colonies are encircled by large cornerstone focal adhesions (FAs). Here, using super-resolution imaging, the authors describe features in the nanoscale makeup of these stable FAs such as inverted vinculin, lateral talin segregation and distinct kank protein distributions. |
format |
article |
author |
Aki Stubb Camilo Guzmán Elisa Närvä Jesse Aaron Teng-Leong Chew Markku Saari Mitro Miihkinen Guillaume Jacquemet Johanna Ivaska |
author_facet |
Aki Stubb Camilo Guzmán Elisa Närvä Jesse Aaron Teng-Leong Chew Markku Saari Mitro Miihkinen Guillaume Jacquemet Johanna Ivaska |
author_sort |
Aki Stubb |
title |
Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells |
title_short |
Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells |
title_full |
Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells |
title_fullStr |
Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells |
title_full_unstemmed |
Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells |
title_sort |
superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/054ff7d405564aaf959a9efd06915fc4 |
work_keys_str_mv |
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_version_ |
1718382128232660992 |