Emerging hantaviruses in Central Argentina: First case of Hantavirus Pulmonary Syndrome caused by Alto Paraguay virus, and a novel orthohantavirus in Scapteromys aquaticus rodent.

Orthohantaviruses are emerging rodent-borne pathogens that cause Hantavirus Pulmonary Syndrome in humans. They have a wide range of rodent reservoir hosts and are transmitted to humans through aerosolized viral particles generated by the excretions of infected individuals. Since the first descriptio...

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Autores principales: Carla Bellomo, Daniel Oscar Alonso, Tamara Ricardo, Rocío Coelho, Sebastián Kehl, Natalia Periolo, Viviana Azogaray, Natalia Casas, Mariano Ottonelli, Laura Cristina Bergero, María Carolina Cudós, María Andrea Previtali, Valeria Paula Martinez
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Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/0550e7de464e430b8a0274906c42e2ee
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spelling oai:doaj.org-article:0550e7de464e430b8a0274906c42e2ee2021-12-02T20:23:58ZEmerging hantaviruses in Central Argentina: First case of Hantavirus Pulmonary Syndrome caused by Alto Paraguay virus, and a novel orthohantavirus in Scapteromys aquaticus rodent.1935-27271935-273510.1371/journal.pntd.0009842https://doaj.org/article/0550e7de464e430b8a0274906c42e2ee2021-11-01T00:00:00Zhttps://doi.org/10.1371/journal.pntd.0009842https://doaj.org/toc/1935-2727https://doaj.org/toc/1935-2735Orthohantaviruses are emerging rodent-borne pathogens that cause Hantavirus Pulmonary Syndrome in humans. They have a wide range of rodent reservoir hosts and are transmitted to humans through aerosolized viral particles generated by the excretions of infected individuals. Since the first description of HPS in Argentina, new hantaviruses have been reported throughout the country, most of which are pathogenic to humans. We present here the first HPS case infected with Alto Paraguay virus reported in Argentina. Until now, Alto Paraguay virus was considered a non-pathogenic orthohantavirus since it was identified in a rodent, Holochilus chacarius. In addition to this, with the goal of identifying potential hantavirus host species in the province of Santa Fe, we finally describe a novel orthohantavirus found in the native rodent Scapteromys aquaticus, which differed from other hantaviruses described in the country so far. Our findings implicate an epidemiological warning regarding these new orthohantaviruses circulating in Central Argentina as well as new rodent species that must be considered as hosts from now on.Carla BellomoDaniel Oscar AlonsoTamara RicardoRocío CoelhoSebastián KehlNatalia PerioloViviana AzogarayNatalia CasasMariano OttonelliLaura Cristina BergeroMaría Carolina CudósMaría Andrea PrevitaliValeria Paula MartinezPublic Library of Science (PLoS)articleArctic medicine. Tropical medicineRC955-962Public aspects of medicineRA1-1270ENPLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009842 (2021)
institution DOAJ
collection DOAJ
language EN
topic Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
spellingShingle Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
Carla Bellomo
Daniel Oscar Alonso
Tamara Ricardo
Rocío Coelho
Sebastián Kehl
Natalia Periolo
Viviana Azogaray
Natalia Casas
Mariano Ottonelli
Laura Cristina Bergero
María Carolina Cudós
María Andrea Previtali
Valeria Paula Martinez
Emerging hantaviruses in Central Argentina: First case of Hantavirus Pulmonary Syndrome caused by Alto Paraguay virus, and a novel orthohantavirus in Scapteromys aquaticus rodent.
description Orthohantaviruses are emerging rodent-borne pathogens that cause Hantavirus Pulmonary Syndrome in humans. They have a wide range of rodent reservoir hosts and are transmitted to humans through aerosolized viral particles generated by the excretions of infected individuals. Since the first description of HPS in Argentina, new hantaviruses have been reported throughout the country, most of which are pathogenic to humans. We present here the first HPS case infected with Alto Paraguay virus reported in Argentina. Until now, Alto Paraguay virus was considered a non-pathogenic orthohantavirus since it was identified in a rodent, Holochilus chacarius. In addition to this, with the goal of identifying potential hantavirus host species in the province of Santa Fe, we finally describe a novel orthohantavirus found in the native rodent Scapteromys aquaticus, which differed from other hantaviruses described in the country so far. Our findings implicate an epidemiological warning regarding these new orthohantaviruses circulating in Central Argentina as well as new rodent species that must be considered as hosts from now on.
format article
author Carla Bellomo
Daniel Oscar Alonso
Tamara Ricardo
Rocío Coelho
Sebastián Kehl
Natalia Periolo
Viviana Azogaray
Natalia Casas
Mariano Ottonelli
Laura Cristina Bergero
María Carolina Cudós
María Andrea Previtali
Valeria Paula Martinez
author_facet Carla Bellomo
Daniel Oscar Alonso
Tamara Ricardo
Rocío Coelho
Sebastián Kehl
Natalia Periolo
Viviana Azogaray
Natalia Casas
Mariano Ottonelli
Laura Cristina Bergero
María Carolina Cudós
María Andrea Previtali
Valeria Paula Martinez
author_sort Carla Bellomo
title Emerging hantaviruses in Central Argentina: First case of Hantavirus Pulmonary Syndrome caused by Alto Paraguay virus, and a novel orthohantavirus in Scapteromys aquaticus rodent.
title_short Emerging hantaviruses in Central Argentina: First case of Hantavirus Pulmonary Syndrome caused by Alto Paraguay virus, and a novel orthohantavirus in Scapteromys aquaticus rodent.
title_full Emerging hantaviruses in Central Argentina: First case of Hantavirus Pulmonary Syndrome caused by Alto Paraguay virus, and a novel orthohantavirus in Scapteromys aquaticus rodent.
title_fullStr Emerging hantaviruses in Central Argentina: First case of Hantavirus Pulmonary Syndrome caused by Alto Paraguay virus, and a novel orthohantavirus in Scapteromys aquaticus rodent.
title_full_unstemmed Emerging hantaviruses in Central Argentina: First case of Hantavirus Pulmonary Syndrome caused by Alto Paraguay virus, and a novel orthohantavirus in Scapteromys aquaticus rodent.
title_sort emerging hantaviruses in central argentina: first case of hantavirus pulmonary syndrome caused by alto paraguay virus, and a novel orthohantavirus in scapteromys aquaticus rodent.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/0550e7de464e430b8a0274906c42e2ee
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