Prognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study

Abstract Aim The present study aimed to explore these characteristics, particularly thin-cap fibroatheroma (TCFA), in relation to residual syntax score (rSS) in patients who presented with acute MI. Methods and outcomes A total of 434 consecutive patients with MI aged ≥18 years who had STEMI underwe...

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Autores principales:	Xiaoxiao Zhao, Ying Wang, Runzhen Chen, Jiannan Li, Jinying Zhou, Chen Liu, Peng Zhou, Zhaoxue Sheng, Yi Chen, Li Song, Hanjun Zhao, Hongbing Yan
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Optical coherence tomography Residual syntax score Thin-cap fibroatheroma Prognosis value Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/055c9390fe5846abb65ea2e79c06894a
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spelling	oai:doaj.org-article:055c9390fe5846abb65ea2e79c06894a2021-11-14T12:28:47ZPrognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study10.1186/s12959-021-00329-z1477-9560https://doaj.org/article/055c9390fe5846abb65ea2e79c06894a2021-11-01T00:00:00Zhttps://doi.org/10.1186/s12959-021-00329-zhttps://doaj.org/toc/1477-9560Abstract Aim The present study aimed to explore these characteristics, particularly thin-cap fibroatheroma (TCFA), in relation to residual syntax score (rSS) in patients who presented with acute MI. Methods and outcomes A total of 434 consecutive patients with MI aged ≥18 years who had STEMI underwent primary PCI. Notably, compared with other subgroups, the presence of TCFA in culprit lesions and a higher level of rSS, were significantly associated with MACE. When rSS was divided into three groups, high rSS levels were associated with a higher incidence of MACE, in the subgroups of without TCFA (P = 0.005), plaque erosion (P = 0.045), macrophage infiltration (P = 0.026), and calcification (P = 0.002). AUC of ROC curve was 0.794 and 0.816, whereas the AUC of the survival ROC was 0.798 and 0.846. Conclusion The results of this study could be used in clinical practice to support risk stratification. Trial registration This study was registered at ClinicalTrials.gov as NCT03593928 .Xiaoxiao ZhaoYing WangRunzhen ChenJiannan LiJinying ZhouChen LiuPeng ZhouZhaoxue ShengYi ChenLi SongHanjun ZhaoHongbing YanBMCarticleOptical coherence tomographyResidual syntax scoreThin-cap fibroatheromaPrognosis valueDiseases of the blood and blood-forming organsRC633-647.5ENThrombosis Journal, Vol 19, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Optical coherence tomography Residual syntax score Thin-cap fibroatheroma Prognosis value Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	Optical coherence tomography Residual syntax score Thin-cap fibroatheroma Prognosis value Diseases of the blood and blood-forming organs RC633-647.5 Xiaoxiao Zhao Ying Wang Runzhen Chen Jiannan Li Jinying Zhou Chen Liu Peng Zhou Zhaoxue Sheng Yi Chen Li Song Hanjun Zhao Hongbing Yan Prognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study
description	Abstract Aim The present study aimed to explore these characteristics, particularly thin-cap fibroatheroma (TCFA), in relation to residual syntax score (rSS) in patients who presented with acute MI. Methods and outcomes A total of 434 consecutive patients with MI aged ≥18 years who had STEMI underwent primary PCI. Notably, compared with other subgroups, the presence of TCFA in culprit lesions and a higher level of rSS, were significantly associated with MACE. When rSS was divided into three groups, high rSS levels were associated with a higher incidence of MACE, in the subgroups of without TCFA (P = 0.005), plaque erosion (P = 0.045), macrophage infiltration (P = 0.026), and calcification (P = 0.002). AUC of ROC curve was 0.794 and 0.816, whereas the AUC of the survival ROC was 0.798 and 0.846. Conclusion The results of this study could be used in clinical practice to support risk stratification. Trial registration This study was registered at ClinicalTrials.gov as NCT03593928 .
format	article
author	Xiaoxiao Zhao Ying Wang Runzhen Chen Jiannan Li Jinying Zhou Chen Liu Peng Zhou Zhaoxue Sheng Yi Chen Li Song Hanjun Zhao Hongbing Yan
author_facet	Xiaoxiao Zhao Ying Wang Runzhen Chen Jiannan Li Jinying Zhou Chen Liu Peng Zhou Zhaoxue Sheng Yi Chen Li Song Hanjun Zhao Hongbing Yan
author_sort	Xiaoxiao Zhao
title	Prognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study
title_short	Prognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study
title_full	Prognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study
title_fullStr	Prognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study
title_full_unstemmed	Prognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study
title_sort	prognostic value of characteristics of plaque combined with residual syntax score among patients with stemi undergoing primary pci: an intravascular optical coherence tomography study
publisher	BMC
publishDate	2021
url	https://doaj.org/article/055c9390fe5846abb65ea2e79c06894a
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Prognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study

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