DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci
The mechanism regulating DNA repair in late anaphase or telophase is not yet clear. Here authors reveal that DNA double strand breaks in telophase causes a partial reversal of sister chromosome segregation which could create an opportunity of using the sister for repair in telophase.
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Nature Portfolio
2019
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oai:doaj.org-article:056a736d2c904c838127babaa20803742021-12-02T14:40:01ZDNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci10.1038/s41467-019-10742-82041-1723https://doaj.org/article/056a736d2c904c838127babaa20803742019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10742-8https://doaj.org/toc/2041-1723The mechanism regulating DNA repair in late anaphase or telophase is not yet clear. Here authors reveal that DNA double strand breaks in telophase causes a partial reversal of sister chromosome segregation which could create an opportunity of using the sister for repair in telophase.Jessel Ayra-PlasenciaFélix MachínNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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Science Q Jessel Ayra-Plasencia Félix Machín DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci |
description |
The mechanism regulating DNA repair in late anaphase or telophase is not yet clear. Here authors reveal that DNA double strand breaks in telophase causes a partial reversal of sister chromosome segregation which could create an opportunity of using the sister for repair in telophase. |
format |
article |
author |
Jessel Ayra-Plasencia Félix Machín |
author_facet |
Jessel Ayra-Plasencia Félix Machín |
author_sort |
Jessel Ayra-Plasencia |
title |
DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci |
title_short |
DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci |
title_full |
DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci |
title_fullStr |
DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci |
title_full_unstemmed |
DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci |
title_sort |
dna double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/056a736d2c904c838127babaa2080374 |
work_keys_str_mv |
AT jesselayraplasencia dnadoublestrandbreaksintelophaseleadtocoalescencebetweensegregatedsisterchromatidloci AT felixmachin dnadoublestrandbreaksintelophaseleadtocoalescencebetweensegregatedsisterchromatidloci |
_version_ |
1718390395892662272 |