THE ENZYMATIC STATUS FEATURES IN BLOOD LYMPHOCYTES IN CHILDREN WITH DYSFUNCTIONAL DISORDERS OF BILIARY TRACT AND THEIR ASSOCIATION WITH GIARDIASIS

N the study of NAD(P)-dependent dehydrogenases activity in blood lymphocytes in children with dysfunctional disorders of the biliary tract (DDBT) and. DDBT in association with giardiasis detected significant changes in the intracellular metabolism. In children with DDBT in blood lymphocytes the leve...

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Autores principales: N. G. Muravyeva, A. A. Savchenko, V. T. Manchuk
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2012
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Acceso en línea:https://doaj.org/article/05770f608d8443b8a36abefc2d8083e8
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spelling oai:doaj.org-article:05770f608d8443b8a36abefc2d8083e82021-11-23T06:14:17ZTHE ENZYMATIC STATUS FEATURES IN BLOOD LYMPHOCYTES IN CHILDREN WITH DYSFUNCTIONAL DISORDERS OF BILIARY TRACT AND THEIR ASSOCIATION WITH GIARDIASIS2541-94202587-9596https://doaj.org/article/05770f608d8443b8a36abefc2d8083e82012-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/749https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596N the study of NAD(P)-dependent dehydrogenases activity in blood lymphocytes in children with dysfunctional disorders of the biliary tract (DDBT) and. DDBT in association with giardiasis detected significant changes in the intracellular metabolism. In children with DDBT in blood lymphocytes the levels of substrate flow decreased at the terminal reactions of glycolysis and. the tricarboxylic acid cycle, which determines the inhibition, respectively, anaerobic and aerobic cellular respiration. It's been established that in blood lymphocytes of children with DDBT, associated with giardiasis, the activity of enzymes determining the state of aerobic respiration is reduced, while maintaining the normal level of intensity of the terminal reactions of anaerobic glycolysis. Regardless of the presence or absence of giardiasis in children with DDBT the activity of pentose phosphate cycle is reduced which characterizes the inhibition of the reactions of macromolecular synthesis.N. G. MuravyevaA. A. SavchenkoV. T. ManchukScientific Сentre for Family Health and Human Reproduction Problemsarticledysfunctional disorders of the biliary tractgiardiasismetabolismlymphocytesScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 48-51 (2012)
institution DOAJ
collection DOAJ
language RU
topic dysfunctional disorders of the biliary tract
giardiasis
metabolism
lymphocytes
Science
Q
spellingShingle dysfunctional disorders of the biliary tract
giardiasis
metabolism
lymphocytes
Science
Q
N. G. Muravyeva
A. A. Savchenko
V. T. Manchuk
THE ENZYMATIC STATUS FEATURES IN BLOOD LYMPHOCYTES IN CHILDREN WITH DYSFUNCTIONAL DISORDERS OF BILIARY TRACT AND THEIR ASSOCIATION WITH GIARDIASIS
description N the study of NAD(P)-dependent dehydrogenases activity in blood lymphocytes in children with dysfunctional disorders of the biliary tract (DDBT) and. DDBT in association with giardiasis detected significant changes in the intracellular metabolism. In children with DDBT in blood lymphocytes the levels of substrate flow decreased at the terminal reactions of glycolysis and. the tricarboxylic acid cycle, which determines the inhibition, respectively, anaerobic and aerobic cellular respiration. It's been established that in blood lymphocytes of children with DDBT, associated with giardiasis, the activity of enzymes determining the state of aerobic respiration is reduced, while maintaining the normal level of intensity of the terminal reactions of anaerobic glycolysis. Regardless of the presence or absence of giardiasis in children with DDBT the activity of pentose phosphate cycle is reduced which characterizes the inhibition of the reactions of macromolecular synthesis.
format article
author N. G. Muravyeva
A. A. Savchenko
V. T. Manchuk
author_facet N. G. Muravyeva
A. A. Savchenko
V. T. Manchuk
author_sort N. G. Muravyeva
title THE ENZYMATIC STATUS FEATURES IN BLOOD LYMPHOCYTES IN CHILDREN WITH DYSFUNCTIONAL DISORDERS OF BILIARY TRACT AND THEIR ASSOCIATION WITH GIARDIASIS
title_short THE ENZYMATIC STATUS FEATURES IN BLOOD LYMPHOCYTES IN CHILDREN WITH DYSFUNCTIONAL DISORDERS OF BILIARY TRACT AND THEIR ASSOCIATION WITH GIARDIASIS
title_full THE ENZYMATIC STATUS FEATURES IN BLOOD LYMPHOCYTES IN CHILDREN WITH DYSFUNCTIONAL DISORDERS OF BILIARY TRACT AND THEIR ASSOCIATION WITH GIARDIASIS
title_fullStr THE ENZYMATIC STATUS FEATURES IN BLOOD LYMPHOCYTES IN CHILDREN WITH DYSFUNCTIONAL DISORDERS OF BILIARY TRACT AND THEIR ASSOCIATION WITH GIARDIASIS
title_full_unstemmed THE ENZYMATIC STATUS FEATURES IN BLOOD LYMPHOCYTES IN CHILDREN WITH DYSFUNCTIONAL DISORDERS OF BILIARY TRACT AND THEIR ASSOCIATION WITH GIARDIASIS
title_sort enzymatic status features in blood lymphocytes in children with dysfunctional disorders of biliary tract and their association with giardiasis
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2012
url https://doaj.org/article/05770f608d8443b8a36abefc2d8083e8
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